Correlation of blood lead level and intelligence quotient in children
Background Lead poisoning is a source of health problems in humans. A chronic complication oflead poisoning in children is permanent intellectual impairment. Objective To assess for a correlation of blood lead levels and intelligence quotient (IQ) in children. Methods A cross-sectional study was per...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Indonesian Pediatric Society Publishing House
2014-06-01
|
| Series: | Paediatrica Indonesiana |
| Subjects: | |
| Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/407 |
| _version_ | 1819132906124083200 |
|---|---|
| author | Lilian Gunawan Nurhayati Masloman |
| author_facet | Lilian Gunawan Nurhayati Masloman |
| author_sort | Lilian Gunawan |
| collection | DOAJ |
| description | Background Lead poisoning is a source of health problems in
humans. A chronic complication oflead poisoning in children is
permanent intellectual impairment.
Objective To assess for a correlation of blood lead levels and
intelligence quotient (IQ) in children.
Methods A cross-sectional study was performed in children aged
6 to 8 years in th e Talawaan (a rural area) and Wenang (an urban
area) Distticts, North Sulawesi, from April to July 2012. Blood lead
levels were measured using the graphite furnace atomic absorption
spectrometry technique; and intelligence was meas ured with the
Wechsler Intelligence Scale for Children-Indonesian version.
Results There were 50 subjects from the Talawaan District and 54
subjects from the Wenang Disttict in this study. The mean blood
lead level in the Talawaan District subjects was significantly higher
than that of the Wenang Disttict subjects [25.8 (SD 16.98) μgidL
vs 11.4 (SD 13.81) μgidL, respectively; (P<0.001)]. There was a
weak negative correlation between blood lead level and IQ in the
Talawaan Disttict children (P= 0.038; r= -0.3). As such, there was
a 0.05 IQ point decrement associated with each increase of 1 μ gidL
in blood lead level in Talawaan District children. However, there
was no correlation between blood lead level and IQ in the Wenang
Disttict children (P=0.42; r =0.03).
Conclusion There is a weak negative correlation between blood
lead level and IQ in children living in a rural area, howevei; this
correlation is not found in children living in an urban area. |
| first_indexed | 2024-12-22T09:38:50Z |
| format | Article |
| id | doaj.art-872214f26c1942b5b257536d286a3cca |
| institution | Directory Open Access Journal |
| issn | 0030-9311 2338-476X |
| language | English |
| last_indexed | 2024-12-22T09:38:50Z |
| publishDate | 2014-06-01 |
| publisher | Indonesian Pediatric Society Publishing House |
| record_format | Article |
| series | Paediatrica Indonesiana |
| spelling | doaj.art-872214f26c1942b5b257536d286a3cca2022-12-21T18:30:45ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2014-06-015431273110.14238/pi54.3.2014.127-31298Correlation of blood lead level and intelligence quotient in childrenLilian Gunawan0Nurhayati Masloman1Department of Child Health, Sam Ratulangi University Medical School, Prof. Dr. R. D. Kandou HospitalDepartment of Child Health, Sam Ratulangi University Medical School, Prof. Dr. R. D. Kandou HospitalBackground Lead poisoning is a source of health problems in humans. A chronic complication oflead poisoning in children is permanent intellectual impairment. Objective To assess for a correlation of blood lead levels and intelligence quotient (IQ) in children. Methods A cross-sectional study was performed in children aged 6 to 8 years in th e Talawaan (a rural area) and Wenang (an urban area) Distticts, North Sulawesi, from April to July 2012. Blood lead levels were measured using the graphite furnace atomic absorption spectrometry technique; and intelligence was meas ured with the Wechsler Intelligence Scale for Children-Indonesian version. Results There were 50 subjects from the Talawaan District and 54 subjects from the Wenang Disttict in this study. The mean blood lead level in the Talawaan District subjects was significantly higher than that of the Wenang Disttict subjects [25.8 (SD 16.98) μgidL vs 11.4 (SD 13.81) μgidL, respectively; (P<0.001)]. There was a weak negative correlation between blood lead level and IQ in the Talawaan Disttict children (P= 0.038; r= -0.3). As such, there was a 0.05 IQ point decrement associated with each increase of 1 μ gidL in blood lead level in Talawaan District children. However, there was no correlation between blood lead level and IQ in the Wenang Disttict children (P=0.42; r =0.03). Conclusion There is a weak negative correlation between blood lead level and IQ in children living in a rural area, howevei; this correlation is not found in children living in an urban area.https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/407lead, IQ, children |
| spellingShingle | Lilian Gunawan Nurhayati Masloman Correlation of blood lead level and intelligence quotient in children Paediatrica Indonesiana lead, IQ, children |
| title | Correlation of blood lead level and intelligence quotient in children |
| title_full | Correlation of blood lead level and intelligence quotient in children |
| title_fullStr | Correlation of blood lead level and intelligence quotient in children |
| title_full_unstemmed | Correlation of blood lead level and intelligence quotient in children |
| title_short | Correlation of blood lead level and intelligence quotient in children |
| title_sort | correlation of blood lead level and intelligence quotient in children |
| topic | lead, IQ, children |
| url | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/407 |
| work_keys_str_mv | AT liliangunawan correlationofbloodleadlevelandintelligencequotientinchildren AT nurhayatimasloman correlationofbloodleadlevelandintelligencequotientinchildren |