Metastatic eccrine porocarcinoma: report of a case and review of the literature

<p>Abstract</p> <p>Eccrine porocarcinoma (EPC) is a rare type of skin cancer arising from the intraepidermal portion of eccrine sweat glands or acrosyringium, representing 0.005-0.01% of all cutaneous tumors. About 20% of EPC will recur and about 20% will metastasize to regional ly...

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Main Authors: Di Cecilia Maria, Chiofalo Maria, Di Monta Gianluca, Anniciello Anna, Caracò Corrado, Marone Ugo, Mozzillo Nicola
Format: Article
Language:English
Published: BMC 2011-03-01
Series:World Journal of Surgical Oncology
Online Access:http://www.wjso.com/content/9/1/32
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author Di Cecilia Maria
Chiofalo Maria
Di Monta Gianluca
Anniciello Anna
Caracò Corrado
Marone Ugo
Mozzillo Nicola
author_facet Di Cecilia Maria
Chiofalo Maria
Di Monta Gianluca
Anniciello Anna
Caracò Corrado
Marone Ugo
Mozzillo Nicola
author_sort Di Cecilia Maria
collection DOAJ
description <p>Abstract</p> <p>Eccrine porocarcinoma (EPC) is a rare type of skin cancer arising from the intraepidermal portion of eccrine sweat glands or acrosyringium, representing 0.005-0.01% of all cutaneous tumors. About 20% of EPC will recur and about 20% will metastasize to regional lymph nodes. There is a mortality rate of 67% in patients with lymph node metastases. Although rare, the occurrence of distant metastases has been reported.</p> <p>We report a case of patient with EPC of the left arm, with axillary nodal involvement and subsequent local relapse, treated by complete lymph node dissection and electrochemotherapy (ECT).</p> <p>EPC is an unusual tumor to diagnose. Neither chemotherapy nor radiation therapy has been proven to be of clinical benefit in treating metastatic disease. Although in the current case the short follow-up period is a limitation, we consider in the management of EPC a therapeutic approach involving surgery and ECT, because of its aggressive potential for loregional metastatic spread.</p>
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spelling doaj.art-8725dc7948f54acc8ae879881ca051302022-12-21T21:52:39ZengBMCWorld Journal of Surgical Oncology1477-78192011-03-01913210.1186/1477-7819-9-32Metastatic eccrine porocarcinoma: report of a case and review of the literatureDi Cecilia MariaChiofalo MariaDi Monta GianlucaAnniciello AnnaCaracò CorradoMarone UgoMozzillo Nicola<p>Abstract</p> <p>Eccrine porocarcinoma (EPC) is a rare type of skin cancer arising from the intraepidermal portion of eccrine sweat glands or acrosyringium, representing 0.005-0.01% of all cutaneous tumors. About 20% of EPC will recur and about 20% will metastasize to regional lymph nodes. There is a mortality rate of 67% in patients with lymph node metastases. Although rare, the occurrence of distant metastases has been reported.</p> <p>We report a case of patient with EPC of the left arm, with axillary nodal involvement and subsequent local relapse, treated by complete lymph node dissection and electrochemotherapy (ECT).</p> <p>EPC is an unusual tumor to diagnose. Neither chemotherapy nor radiation therapy has been proven to be of clinical benefit in treating metastatic disease. Although in the current case the short follow-up period is a limitation, we consider in the management of EPC a therapeutic approach involving surgery and ECT, because of its aggressive potential for loregional metastatic spread.</p>http://www.wjso.com/content/9/1/32
spellingShingle Di Cecilia Maria
Chiofalo Maria
Di Monta Gianluca
Anniciello Anna
Caracò Corrado
Marone Ugo
Mozzillo Nicola
Metastatic eccrine porocarcinoma: report of a case and review of the literature
World Journal of Surgical Oncology
title Metastatic eccrine porocarcinoma: report of a case and review of the literature
title_full Metastatic eccrine porocarcinoma: report of a case and review of the literature
title_fullStr Metastatic eccrine porocarcinoma: report of a case and review of the literature
title_full_unstemmed Metastatic eccrine porocarcinoma: report of a case and review of the literature
title_short Metastatic eccrine porocarcinoma: report of a case and review of the literature
title_sort metastatic eccrine porocarcinoma report of a case and review of the literature
url http://www.wjso.com/content/9/1/32
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