Severe Cryptogenic Multifocal Ulcerous Stenosing Enteritis. A Report of Three Cases and Review of the Literature
Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare condition characterised by chronic or relapsing moderate ileous episodes resulting from multiple small intestinal strictures, multiple shallow ulcers of the small bowel and favourable therapeutical effect of glucocorticosteroids....
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| Format: | Article |
| Language: | English |
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Karolinum Press
2010-01-01
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| Series: | Acta Medica |
| Subjects: | |
| Online Access: | https://actamedica.lfhk.cuni.cz/53/1/0025/ |
| _version_ | 1818291760165552128 |
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| author | Darina Kohoutová Jan Bureš Věra Tyčová Jolana Bártová Ilja Tachecí Stanislav Rejchrt Zdeněk Vacek Rudolf Repák Marcela Kopáčová |
| author_facet | Darina Kohoutová Jan Bureš Věra Tyčová Jolana Bártová Ilja Tachecí Stanislav Rejchrt Zdeněk Vacek Rudolf Repák Marcela Kopáčová |
| author_sort | Darina Kohoutová |
| collection | DOAJ |
| description | Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare condition characterised by chronic or relapsing moderate ileous episodes resulting from multiple small intestinal strictures, multiple shallow ulcers of the small bowel and favourable therapeutical effect of glucocorticosteroids. The aim of this paper was to evaluate three cases of CMUSE diagnosed within 10 years at a tertiary gastroenterology centre. Three females (35, 50, 60 years) were presented with colicky pain, repeated moderate ileous episodes and weight loss. Multiple fibrous strictures and ulcers of the small bowel were found. All three patients responded to glucocorticosteroid treatment. Tandem tight jejunal stenoses were dilated endoscopically by means of double balloon enteroscopy. In conclusion, CMUSE should always be considered when chronic moderate ileous episodes and multiple small intestinal strictures and ulcers of uncertain aetiology are found. Double balloon enteroscopy enables precise diagnostic work, possible endoscopic treatment of stenoses, may obviate the need for surgery and prevent excessive small bowel resections. |
| first_indexed | 2024-12-13T02:49:11Z |
| format | Article |
| id | doaj.art-872d43d65526420b91e0369217d36803 |
| institution | Directory Open Access Journal |
| issn | 1211-4286 1805-9694 |
| language | English |
| last_indexed | 2024-12-13T02:49:11Z |
| publishDate | 2010-01-01 |
| publisher | Karolinum Press |
| record_format | Article |
| series | Acta Medica |
| spelling | doaj.art-872d43d65526420b91e0369217d368032022-12-22T00:02:07ZengKarolinum PressActa Medica1211-42861805-96942010-01-01531252910.14712/18059694.2016.59Severe Cryptogenic Multifocal Ulcerous Stenosing Enteritis. A Report of Three Cases and Review of the LiteratureDarina Kohoutová0Jan Bureš1Věra Tyčová2Jolana Bártová3Ilja Tachecí4Stanislav Rejchrt5Zdeněk Vacek6Rudolf Repák7Marcela Kopáčová8Charles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, 2nd Department of Internal Medicine, Division of Gastroenterology, Hradec Králové, Czech RepublicCharles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, 2nd Department of Internal Medicine, Division of Gastroenterology, Hradec Králové, Czech RepublicCharles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, The Fingerland Department of Pathology, Hradec Králové, Czech RepublicCharles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, 2nd Department of Internal Medicine, Division of Gastroenterology, Hradec Králové, Czech RepublicCharles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, 2nd Department of Internal Medicine, Division of Gastroenterology, Hradec Králové, Czech RepublicCharles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, 2nd Department of Internal Medicine, Division of Gastroenterology, Hradec Králové, Czech RepublicCharles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, Department of Radiology, Hradec Králové, Czech RepublicCharles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, 2nd Department of Internal Medicine, Division of Gastroenterology, Hradec Králové, Czech RepublicCharles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, 2nd Department of Internal Medicine, Division of Gastroenterology, Hradec Králové, Czech RepublicCryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare condition characterised by chronic or relapsing moderate ileous episodes resulting from multiple small intestinal strictures, multiple shallow ulcers of the small bowel and favourable therapeutical effect of glucocorticosteroids. The aim of this paper was to evaluate three cases of CMUSE diagnosed within 10 years at a tertiary gastroenterology centre. Three females (35, 50, 60 years) were presented with colicky pain, repeated moderate ileous episodes and weight loss. Multiple fibrous strictures and ulcers of the small bowel were found. All three patients responded to glucocorticosteroid treatment. Tandem tight jejunal stenoses were dilated endoscopically by means of double balloon enteroscopy. In conclusion, CMUSE should always be considered when chronic moderate ileous episodes and multiple small intestinal strictures and ulcers of uncertain aetiology are found. Double balloon enteroscopy enables precise diagnostic work, possible endoscopic treatment of stenoses, may obviate the need for surgery and prevent excessive small bowel resections.https://actamedica.lfhk.cuni.cz/53/1/0025/Cryptogenic multifocal ulcerous stenosing enteritisModerate ileous episodesSmall intestinal ulcersGlucocorticosteroids |
| spellingShingle | Darina Kohoutová Jan Bureš Věra Tyčová Jolana Bártová Ilja Tachecí Stanislav Rejchrt Zdeněk Vacek Rudolf Repák Marcela Kopáčová Severe Cryptogenic Multifocal Ulcerous Stenosing Enteritis. A Report of Three Cases and Review of the Literature Acta Medica Cryptogenic multifocal ulcerous stenosing enteritis Moderate ileous episodes Small intestinal ulcers Glucocorticosteroids |
| title | Severe Cryptogenic Multifocal Ulcerous Stenosing Enteritis. A Report of Three Cases and Review of the Literature |
| title_full | Severe Cryptogenic Multifocal Ulcerous Stenosing Enteritis. A Report of Three Cases and Review of the Literature |
| title_fullStr | Severe Cryptogenic Multifocal Ulcerous Stenosing Enteritis. A Report of Three Cases and Review of the Literature |
| title_full_unstemmed | Severe Cryptogenic Multifocal Ulcerous Stenosing Enteritis. A Report of Three Cases and Review of the Literature |
| title_short | Severe Cryptogenic Multifocal Ulcerous Stenosing Enteritis. A Report of Three Cases and Review of the Literature |
| title_sort | severe cryptogenic multifocal ulcerous stenosing enteritis a report of three cases and review of the literature |
| topic | Cryptogenic multifocal ulcerous stenosing enteritis Moderate ileous episodes Small intestinal ulcers Glucocorticosteroids |
| url | https://actamedica.lfhk.cuni.cz/53/1/0025/ |
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