Sarcoidosis developing after COVID‐19: A case report
Abstract COVID‐19 has been implicated in the development of a range of autoimmune diseases and medical consequences. Sarcoidosis is an inflammatory disease with sustained granulomatous inflammation. The possible main pathogenesis of sarcoidosis is a dysregulation between immune response and certain...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-09-01
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| Series: | Respirology Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rcr2.1016 |
| _version_ | 1811282154843275264 |
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| author | Dujrath Somboonviboon Anan Wattanathum Narumon Keorochana Kittisak Wongchansom |
| author_facet | Dujrath Somboonviboon Anan Wattanathum Narumon Keorochana Kittisak Wongchansom |
| author_sort | Dujrath Somboonviboon |
| collection | DOAJ |
| description | Abstract COVID‐19 has been implicated in the development of a range of autoimmune diseases and medical consequences. Sarcoidosis is an inflammatory disease with sustained granulomatous inflammation. The possible main pathogenesis of sarcoidosis is a dysregulation between immune response and certain environmental antigens. We present a case of sarcoidosis as an interesting sequela of COVID‐19. The patient was hospitalized due to SARS‐CoV‐2 without complication. Ten weeks after the illness, his chest computed tomography (CT) showed bilateral hilar, paratracheal and subcarinal lymph node enlargement. Endobronchial ultrasound with transbronchial needle aspiration (EBUS‐TBNA) was performed; pathologic findings were that of well‐formed non‐necrotizing granulomas. Complete eye examination reported panuveitis and papillitis in both eyes. On the basis of these findings, sarcoidosis was diagnosed. Therefore, sarcoidosis developing after COVID‐19 was suggested as a possible link between the viral infection and dysregulation of the inflammation process. However, further studies are needed to confirm this association. |
| first_indexed | 2024-04-13T01:46:38Z |
| format | Article |
| id | doaj.art-87338fceae0a47a4b486ca9a00580c28 |
| institution | Directory Open Access Journal |
| issn | 2051-3380 |
| language | English |
| last_indexed | 2024-04-13T01:46:38Z |
| publishDate | 2022-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Respirology Case Reports |
| spelling | doaj.art-87338fceae0a47a4b486ca9a00580c282022-12-22T03:08:00ZengWileyRespirology Case Reports2051-33802022-09-01109n/an/a10.1002/rcr2.1016Sarcoidosis developing after COVID‐19: A case reportDujrath Somboonviboon0Anan Wattanathum1Narumon Keorochana2Kittisak Wongchansom3Pulmonary and Critical Care Division, Department of Medicine Phramongkutklao Hospital Bangkok ThailandPulmonary and Critical Care Division, Department of Medicine Phramongkutklao Hospital Bangkok ThailandOcular Immunology and Inflammation Division, Department of Ophthalmology Phramongkutklao Hospital Bangkok ThailandDepartment of Pathology Army Institute of Pathology Bangkok ThailandAbstract COVID‐19 has been implicated in the development of a range of autoimmune diseases and medical consequences. Sarcoidosis is an inflammatory disease with sustained granulomatous inflammation. The possible main pathogenesis of sarcoidosis is a dysregulation between immune response and certain environmental antigens. We present a case of sarcoidosis as an interesting sequela of COVID‐19. The patient was hospitalized due to SARS‐CoV‐2 without complication. Ten weeks after the illness, his chest computed tomography (CT) showed bilateral hilar, paratracheal and subcarinal lymph node enlargement. Endobronchial ultrasound with transbronchial needle aspiration (EBUS‐TBNA) was performed; pathologic findings were that of well‐formed non‐necrotizing granulomas. Complete eye examination reported panuveitis and papillitis in both eyes. On the basis of these findings, sarcoidosis was diagnosed. Therefore, sarcoidosis developing after COVID‐19 was suggested as a possible link between the viral infection and dysregulation of the inflammation process. However, further studies are needed to confirm this association.https://doi.org/10.1002/rcr2.1016COVID‐19granulomatoussarcoidosisuveitis |
| spellingShingle | Dujrath Somboonviboon Anan Wattanathum Narumon Keorochana Kittisak Wongchansom Sarcoidosis developing after COVID‐19: A case report Respirology Case Reports COVID‐19 granulomatous sarcoidosis uveitis |
| title | Sarcoidosis developing after COVID‐19: A case report |
| title_full | Sarcoidosis developing after COVID‐19: A case report |
| title_fullStr | Sarcoidosis developing after COVID‐19: A case report |
| title_full_unstemmed | Sarcoidosis developing after COVID‐19: A case report |
| title_short | Sarcoidosis developing after COVID‐19: A case report |
| title_sort | sarcoidosis developing after covid 19 a case report |
| topic | COVID‐19 granulomatous sarcoidosis uveitis |
| url | https://doi.org/10.1002/rcr2.1016 |
| work_keys_str_mv | AT dujrathsomboonviboon sarcoidosisdevelopingaftercovid19acasereport AT ananwattanathum sarcoidosisdevelopingaftercovid19acasereport AT narumonkeorochana sarcoidosisdevelopingaftercovid19acasereport AT kittisakwongchansom sarcoidosisdevelopingaftercovid19acasereport |