The Diagnostic Value of the Leukocyte Shift Index in Purulent-Septic Rhinosinusogenic Complications in Children
The aim of this study was to investigate the diagnostic value of the leukocyte shift index (LSI) in inflammatory pathology of the paranasal sinuses (PNS) with the rhinosinusogenic orbital complications (RSOC) in pediatric patients. Methods and Results: The study involved 50 patients (26 boys and 24...
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| Format: | Article |
| Language: | English |
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International Medical Research and Development Corporation
2021-09-01
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| Series: | International Journal of Biomedicine |
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| Online Access: | http://ijbm.org/articles/i43/ijbm_11(3)_shc.pdf |
| _version_ | 1818369712359211008 |
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| author | Tatiana B. Kuznetsova Maria N. Ponomareva Nadezhda E. Kuznetsova |
| author_facet | Tatiana B. Kuznetsova Maria N. Ponomareva Nadezhda E. Kuznetsova |
| author_sort | Tatiana B. Kuznetsova |
| collection | DOAJ |
| description | The aim of this study was to investigate the diagnostic value of the leukocyte shift index (LSI) in inflammatory pathology of the paranasal sinuses (PNS) with the rhinosinusogenic orbital complications (RSOC) in pediatric patients.
Methods and Results: The study involved 50 patients (26 boys and 24 girls) with diseases of the PNS and RSOC (reactive edema of the eyelids, orbital tissue, and purulent-septic complications of the eyelids and orbit) aged from 1 to 17 years (mean age of 6.66±0.63 years). Group 1 included 29 patients (16 boys and 13 girls) with reactive edema of the eyelids and orbital tissue. Group 2 included 21 patients (10 boys and 11 girls) with purulent-septic RSOC. As a marker for determining the activity of the inflammatory process and the disorders of the immunological reactivity of the body, LSI (leukocyte shift index) was calculated. In general, the LSI value was 1.61±0.21 in Group 1 and 3.45±0.49 in Group 2 (P=0.001). Among patients aged between 3 and 12 years, the LSI was 1.66±0.30 in Group 1 and 3.93±0.79 in Group 2 (P=0.012). The results obtained indicate that LSI can be used to predict purulent-septic RSOC in inflammatory diseases of PNS in patients aged between 3 and 12 years. LSI values from 1.36 to 1.96 may predict the development of reactive edema of the eyelids and orbital tissue; from 3.14 to 4.72 - the development of purulent-septic complications of the eyelids and orbit.
Conclusion: The results obtained can be useful in predicting the clinical course of the RSOC in inflammatory pathology of PNS in patients in the age group of 3-12 years. |
| first_indexed | 2024-12-13T23:28:12Z |
| format | Article |
| id | doaj.art-8736e94a355848f0b8de5badc27bc6d1 |
| institution | Directory Open Access Journal |
| issn | 2158-0510 2158-0529 |
| language | English |
| last_indexed | 2024-12-13T23:28:12Z |
| publishDate | 2021-09-01 |
| publisher | International Medical Research and Development Corporation |
| record_format | Article |
| series | International Journal of Biomedicine |
| spelling | doaj.art-8736e94a355848f0b8de5badc27bc6d12022-12-21T23:27:29ZengInternational Medical Research and Development CorporationInternational Journal of Biomedicine2158-05102158-05292021-09-0111330130410.21103/Article11(3)_ShCThe Diagnostic Value of the Leukocyte Shift Index in Purulent-Septic Rhinosinusogenic Complications in ChildrenTatiana B. Kuznetsova0Maria N. Ponomareva1Nadezhda E. Kuznetsova2Tyumen State Medical University, Tyumen, the Russian FederationTyumen State Medical University, Tyumen, the Russian FederationTyumen State Medical University; Tyumen Region Clinical Hospital No2. Tyumen, the Russian FederationThe aim of this study was to investigate the diagnostic value of the leukocyte shift index (LSI) in inflammatory pathology of the paranasal sinuses (PNS) with the rhinosinusogenic orbital complications (RSOC) in pediatric patients. Methods and Results: The study involved 50 patients (26 boys and 24 girls) with diseases of the PNS and RSOC (reactive edema of the eyelids, orbital tissue, and purulent-septic complications of the eyelids and orbit) aged from 1 to 17 years (mean age of 6.66±0.63 years). Group 1 included 29 patients (16 boys and 13 girls) with reactive edema of the eyelids and orbital tissue. Group 2 included 21 patients (10 boys and 11 girls) with purulent-septic RSOC. As a marker for determining the activity of the inflammatory process and the disorders of the immunological reactivity of the body, LSI (leukocyte shift index) was calculated. In general, the LSI value was 1.61±0.21 in Group 1 and 3.45±0.49 in Group 2 (P=0.001). Among patients aged between 3 and 12 years, the LSI was 1.66±0.30 in Group 1 and 3.93±0.79 in Group 2 (P=0.012). The results obtained indicate that LSI can be used to predict purulent-septic RSOC in inflammatory diseases of PNS in patients aged between 3 and 12 years. LSI values from 1.36 to 1.96 may predict the development of reactive edema of the eyelids and orbital tissue; from 3.14 to 4.72 - the development of purulent-septic complications of the eyelids and orbit. Conclusion: The results obtained can be useful in predicting the clinical course of the RSOC in inflammatory pathology of PNS in patients in the age group of 3-12 years.http://ijbm.org/articles/i43/ijbm_11(3)_shc.pdfparanasal sinusesrhinosinusogenic orbital complicationsleukocyte shift index |
| spellingShingle | Tatiana B. Kuznetsova Maria N. Ponomareva Nadezhda E. Kuznetsova The Diagnostic Value of the Leukocyte Shift Index in Purulent-Septic Rhinosinusogenic Complications in Children International Journal of Biomedicine paranasal sinuses rhinosinusogenic orbital complications leukocyte shift index |
| title | The Diagnostic Value of the Leukocyte Shift Index in Purulent-Septic Rhinosinusogenic Complications in Children |
| title_full | The Diagnostic Value of the Leukocyte Shift Index in Purulent-Septic Rhinosinusogenic Complications in Children |
| title_fullStr | The Diagnostic Value of the Leukocyte Shift Index in Purulent-Septic Rhinosinusogenic Complications in Children |
| title_full_unstemmed | The Diagnostic Value of the Leukocyte Shift Index in Purulent-Septic Rhinosinusogenic Complications in Children |
| title_short | The Diagnostic Value of the Leukocyte Shift Index in Purulent-Septic Rhinosinusogenic Complications in Children |
| title_sort | diagnostic value of the leukocyte shift index in purulent septic rhinosinusogenic complications in children |
| topic | paranasal sinuses rhinosinusogenic orbital complications leukocyte shift index |
| url | http://ijbm.org/articles/i43/ijbm_11(3)_shc.pdf |
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