First Impressions Matter: Immune Imprinting and Antibody Cross-Reactivity in Influenza and SARS-CoV-2

First Impressions Matter: Immune Imprinting and Antibody Cross-Reactivity in Influenza and SARS-CoV-2

Many rigorous studies have shown that early childhood infections leave a lasting imprint on the immune system. The understanding of this phenomenon has expanded significantly since 1960, when Dr. Thomas Francis Jr first coined the term “original antigenic sin”, to account for all previous pathogen e...

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Bibliographic Details
Main Authors: Samantha M. King, Shane P. Bryan, Shannon P. Hilchey, Jiong Wang, Martin S. Zand
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pathogens
Subjects:
influenza
immune imprinting
SARS-CoV-2
antigenic distance
multidimensional assay
cross-reactivity
Online Access:https://www.mdpi.com/2076-0817/12/2/169

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