Thoracic segmental spinal anesthesia for radical nephrectomy in a patient with amyotrophic lateral sclerosis—a case report

Abstract Background Amyotrophic lateral sclerosis (ALS) is a rare but fatal neurodegenerative disease of the motor neurons that causes muscle weakness, atrophy, and eventually respiratory failure and death. Anesthesia in these patients carries the risk of aspiration, altered response to muscle relax...

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Main Authors: Prajnananda Haloi, Rahul Biswas, Ananta Bora
Format: Article
Language:English
Published: SpringerOpen 2023-05-01
Series:Ain Shams Journal of Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s42077-023-00326-6
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author Prajnananda Haloi
Rahul Biswas
Ananta Bora
author_facet Prajnananda Haloi
Rahul Biswas
Ananta Bora
author_sort Prajnananda Haloi
collection DOAJ
description Abstract Background Amyotrophic lateral sclerosis (ALS) is a rare but fatal neurodegenerative disease of the motor neurons that causes muscle weakness, atrophy, and eventually respiratory failure and death. Anesthesia in these patients carries the risk of aspiration, altered response to muscle relaxants and opioids, ventilatory depression, and neurotoxicity to local anesthetics. Thoracic segmental spinal anesthesia may be a viable alternative to general anesthesia in upper abdominal surgeries in ALS patients. Case presentation A 38-year-old patient with ALS diagnosed with a left renal mass of mitotic origin was scheduled for radical nephrectomy after an evaluation. Thoracic segmental spinal anesthesia was planned for the patient. The surgery and perioperative period were uneventful, and postoperative analgesic consumption was minimal. The patient was discharged without any progress in his neurodegenerative state. Conclusions Our experience with thoracic segmental spinal anesthesia for nephrectomy in this ALS has been satisfactory. Our goals of maintaining hemodynamic stability, avoiding respiratory depression, and limiting further neurological impairment were all achieved. Further studies are needed to establish thoracic segmental spinal anesthesia as a better modality for such cases.
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spelling doaj.art-873c8d1ec8a04c4988404d6eba35a1822023-05-21T11:09:23ZengSpringerOpenAin Shams Journal of Anesthesiology2090-925X2023-05-011511410.1186/s42077-023-00326-6Thoracic segmental spinal anesthesia for radical nephrectomy in a patient with amyotrophic lateral sclerosis—a case reportPrajnananda Haloi0Rahul Biswas1Ananta Bora2Anaesthesiology and Critical Care, GNRC MedicalAnaesthesiology and Critical Care, GNRC MedicalAnaesthesiology and Critical Care, GNRC MedicalAbstract Background Amyotrophic lateral sclerosis (ALS) is a rare but fatal neurodegenerative disease of the motor neurons that causes muscle weakness, atrophy, and eventually respiratory failure and death. Anesthesia in these patients carries the risk of aspiration, altered response to muscle relaxants and opioids, ventilatory depression, and neurotoxicity to local anesthetics. Thoracic segmental spinal anesthesia may be a viable alternative to general anesthesia in upper abdominal surgeries in ALS patients. Case presentation A 38-year-old patient with ALS diagnosed with a left renal mass of mitotic origin was scheduled for radical nephrectomy after an evaluation. Thoracic segmental spinal anesthesia was planned for the patient. The surgery and perioperative period were uneventful, and postoperative analgesic consumption was minimal. The patient was discharged without any progress in his neurodegenerative state. Conclusions Our experience with thoracic segmental spinal anesthesia for nephrectomy in this ALS has been satisfactory. Our goals of maintaining hemodynamic stability, avoiding respiratory depression, and limiting further neurological impairment were all achieved. Further studies are needed to establish thoracic segmental spinal anesthesia as a better modality for such cases.https://doi.org/10.1186/s42077-023-00326-6Amyotrophic lateral sclerosisThoracic segmental spinal anesthesiaNephrectomyRespiratory depressionNeurodegenerative disease
spellingShingle Prajnananda Haloi
Rahul Biswas
Ananta Bora
Thoracic segmental spinal anesthesia for radical nephrectomy in a patient with amyotrophic lateral sclerosis—a case report
Ain Shams Journal of Anesthesiology
Amyotrophic lateral sclerosis
Thoracic segmental spinal anesthesia
Nephrectomy
Respiratory depression
Neurodegenerative disease
title Thoracic segmental spinal anesthesia for radical nephrectomy in a patient with amyotrophic lateral sclerosis—a case report
title_full Thoracic segmental spinal anesthesia for radical nephrectomy in a patient with amyotrophic lateral sclerosis—a case report
title_fullStr Thoracic segmental spinal anesthesia for radical nephrectomy in a patient with amyotrophic lateral sclerosis—a case report
title_full_unstemmed Thoracic segmental spinal anesthesia for radical nephrectomy in a patient with amyotrophic lateral sclerosis—a case report
title_short Thoracic segmental spinal anesthesia for radical nephrectomy in a patient with amyotrophic lateral sclerosis—a case report
title_sort thoracic segmental spinal anesthesia for radical nephrectomy in a patient with amyotrophic lateral sclerosis a case report
topic Amyotrophic lateral sclerosis
Thoracic segmental spinal anesthesia
Nephrectomy
Respiratory depression
Neurodegenerative disease
url https://doi.org/10.1186/s42077-023-00326-6
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AT rahulbiswas thoracicsegmentalspinalanesthesiaforradicalnephrectomyinapatientwithamyotrophiclateralsclerosisacasereport
AT anantabora thoracicsegmentalspinalanesthesiaforradicalnephrectomyinapatientwithamyotrophiclateralsclerosisacasereport