Abnormal Epigenetic Regulations in the Immunocytes of Sjögren’s Syndrome Patients and Therapeutic Potentials

Abnormal Epigenetic Regulations in the Immunocytes of Sjögren’s Syndrome Patients and Therapeutic Potentials

Sjögren’s syndrome (SjS), characterized by keratoconjunctivitis sicca and dry mouth, is a common autoimmune disease, especially in middle-aged women. The immunopathogenesis of SjS is caused by the sequential infiltration of T and B cells into exocrine glands, including salivary and lacrimal glands....

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Bibliographic Details
Main Authors: Peng Li, Mengwei Han, Xingyu Zhao, Guanqun Ren, Si Mei, Chao Zhong
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
Sjögren’s syndrome
immune infiltration
pro-inflammatory cytokine
epigenetic modification
IFN-related gene
Online Access:https://www.mdpi.com/2073-4409/11/11/1767

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