GABA-A receptor modulating steroids in acute and chronic stress; relevance for cognition and dementia?

GABA-A receptor modulating steroids in acute and chronic stress; relevance for cognition and dementia?

Cognitive dysfunction, dementia and Alzheimer's disease (AD) are increasing as the population worldwide ages. Therapeutics for these conditions is an unmet need. This review focuses on the role of the positive GABA-A receptor modulating steroid allopregnanolone (APα), it's role in underlyi...

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Bibliographic Details
Main Authors:	S.K.S. Bengtsson, T. Bäckström, R. Brinton, R.W. Irwin, M. Johansson, J. Sjöstedt, M.D. Wang
Format:	Article
Language:	English
Published:	Elsevier 2020-05-01
Series:	Neurobiology of Stress
Subjects:	Allopregnanolone GABA-A receptor modulating steroids GABA-A receptor modulating steroid antagonists Learning Memory Dementia
Online Access:	http://www.sciencedirect.com/science/article/pii/S235228951930058X

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