Genetic influences on the development of fibrosis in Crohn’s Disease

Fibrostenotic strictures are an important complication in patients with Crohn’s Disease, very often necessitating surgery. This fibrotic process develops in a genetically susceptible individual, and is influenced by an interplay with environmental, immunological and disease-related factors. A deeper...

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Bibliographic Details
Main Authors: Bram eVerstockt, Isabelle eCleynen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Medicine
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmed.2016.00024/full