Behavioral and Molecular Responses to Exogenous Cannabinoids During Pentylenetetrazol-Induced Convulsions in Male and Female Rats

Behavioral and Molecular Responses to Exogenous Cannabinoids During Pentylenetetrazol-Induced Convulsions in Male and Female Rats

Epilepsy is a disabling, chronic brain disease,affecting ~1% of the World’s population, characterized by recurrent seizures (sudden, uncontrolled brain activity), which may manifest with motor symptoms (e.g., convulsions) or non-motor symptoms. Temporal lobe epilepsies (TLE) compromising the hippoca...

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Bibliographic Details
Main Authors: Antonella Zirotti Rosenberg, Maxs Méndez-Ruette, Mario Gorziglia, Benjamín Alzerreca, Javiera Cabello, Sofía Kaufmann, Lukas Rambousek, Andrés Iturriaga Jofré, Ursula Wyneken, Carlos A. Lafourcade
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
cannabinoids
seizures
epilepsy
beta arrestin-2
hippocampus
dentate gyrus
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.868583/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.868583/full

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