Using Audiometry to Track Atherosclerosis: Measuring a Beneficial Effect of Methotrexate in Rheumatoid Arthritis

Objectives: To correlate audiometry with atherosclerosis. Presbycusis is associated with age and atherosclerosis; a strong correlation might present opportunities to use audiometry to track atherosclerosis disease. Design: The authors tested 87 elderly patients with rheumatoid arthritis (age ran...

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Main Authors: Kylie Greenwald, Maria Greenwald, JoAnn Ball
Format: Article
Language:English
Published: European Medical Journal 2020-07-01
Series:European Medical Journal Rheumatology
Subjects:
Online Access:https://www.emjreviews.com/rheumatology/article/using-audiometry-to-track-atherosclerosis-measuring-a-beneficial-effect-of-methotrexate-in-rheumatoid-arthritis/
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author Kylie Greenwald
Maria Greenwald
JoAnn Ball
author_facet Kylie Greenwald
Maria Greenwald
JoAnn Ball
author_sort Kylie Greenwald
collection DOAJ
description Objectives: To correlate audiometry with atherosclerosis. Presbycusis is associated with age and atherosclerosis; a strong correlation might present opportunities to use audiometry to track atherosclerosis disease. Design: The authors tested 87 elderly patients with rheumatoid arthritis (age range: 80–101 years; median: 86 years) with a history of methotrexate use for over 20 years. After 50 years of age, hearing loss begins slowly and by the age of 90, the majority of the general population require hearing aids. In the 87 elderly participants, however, hearing was remarkably preserved. Results: The observed cohort of 87 individuals showed better hearing than predicted compared to audiometry historically documented in the elderly (p<0.001). The patients tested one to two decades younger than expected on audiometry and 44% of patients qualified for hearing aids instead of the expected 80%, based on age. Conclusion: The known reduction in atherosclerosis with methotrexate use in rheumatoid arthritis may account for this observed preservation of hearing.1,2 As hearing and atherosclerosis are related, the authors further postulated that routine audiometry may provide a cost-effective screening tool for other populations in future atherosclerosis studies.
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spelling doaj.art-874578ddcfa54512ba0ffc0281c7380c2022-12-22T01:30:09ZengEuropean Medical JournalEuropean Medical Journal Rheumatology2056-63952020-07-0171110117Using Audiometry to Track Atherosclerosis: Measuring a Beneficial Effect of Methotrexate in Rheumatoid ArthritisKylie Greenwald0Maria Greenwald1JoAnn Ball2Desert Medical Advances, Palm Desert, California, USADesert Medical Advances, Palm Desert, California, USADesert Medical Advances, Palm Desert, California, USAObjectives: To correlate audiometry with atherosclerosis. Presbycusis is associated with age and atherosclerosis; a strong correlation might present opportunities to use audiometry to track atherosclerosis disease. Design: The authors tested 87 elderly patients with rheumatoid arthritis (age range: 80–101 years; median: 86 years) with a history of methotrexate use for over 20 years. After 50 years of age, hearing loss begins slowly and by the age of 90, the majority of the general population require hearing aids. In the 87 elderly participants, however, hearing was remarkably preserved. Results: The observed cohort of 87 individuals showed better hearing than predicted compared to audiometry historically documented in the elderly (p<0.001). The patients tested one to two decades younger than expected on audiometry and 44% of patients qualified for hearing aids instead of the expected 80%, based on age. Conclusion: The known reduction in atherosclerosis with methotrexate use in rheumatoid arthritis may account for this observed preservation of hearing.1,2 As hearing and atherosclerosis are related, the authors further postulated that routine audiometry may provide a cost-effective screening tool for other populations in future atherosclerosis studies.https://www.emjreviews.com/rheumatology/article/using-audiometry-to-track-atherosclerosis-measuring-a-beneficial-effect-of-methotrexate-in-rheumatoid-arthritis/atherosclerosisaudiometrymethotrexaterheumatoid arthritis
spellingShingle Kylie Greenwald
Maria Greenwald
JoAnn Ball
Using Audiometry to Track Atherosclerosis: Measuring a Beneficial Effect of Methotrexate in Rheumatoid Arthritis
European Medical Journal Rheumatology
atherosclerosis
audiometry
methotrexate
rheumatoid arthritis
title Using Audiometry to Track Atherosclerosis: Measuring a Beneficial Effect of Methotrexate in Rheumatoid Arthritis
title_full Using Audiometry to Track Atherosclerosis: Measuring a Beneficial Effect of Methotrexate in Rheumatoid Arthritis
title_fullStr Using Audiometry to Track Atherosclerosis: Measuring a Beneficial Effect of Methotrexate in Rheumatoid Arthritis
title_full_unstemmed Using Audiometry to Track Atherosclerosis: Measuring a Beneficial Effect of Methotrexate in Rheumatoid Arthritis
title_short Using Audiometry to Track Atherosclerosis: Measuring a Beneficial Effect of Methotrexate in Rheumatoid Arthritis
title_sort using audiometry to track atherosclerosis measuring a beneficial effect of methotrexate in rheumatoid arthritis
topic atherosclerosis
audiometry
methotrexate
rheumatoid arthritis
url https://www.emjreviews.com/rheumatology/article/using-audiometry-to-track-atherosclerosis-measuring-a-beneficial-effect-of-methotrexate-in-rheumatoid-arthritis/
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AT joannball usingaudiometrytotrackatherosclerosismeasuringabeneficialeffectofmethotrexateinrheumatoidarthritis