Accurate digital quantification of tau pathology in progressive supranuclear palsy

Accurate digital quantification of tau pathology in progressive supranuclear palsy

Abstract The development of novel treatments for Progressive Supranuclear Palsy (PSP) is hindered by a knowledge gap of the impact of neurodegenerative neuropathology on brain structure and function. The current standard practice for measuring postmortem tau histology is semi-quantitative assessment...

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Bibliographic Details
Main Authors: Tanrada Pansuwan, Annelies Quaegebeur, Sanne S. Kaalund, Eric Hidari, Mayen Briggs, James B. Rowe, Timothy Rittman
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Acta Neuropathologica Communications
Subjects:
Digital pathology
Random forest
Neurodegenerative diseases
Machine learning
PSP
Online Access:https://doi.org/10.1186/s40478-023-01674-y

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