Effects of the COVID-19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack: A protocol for a systematic review and meta-analysis [version 2; peer review: 3 approved]

Background: The COVID-19 pandemic impacted on health service provision worldwide, including care for acute time sensitive conditions. Stroke and transient ischaemic attacks (TIA) are particularly vulnerable to pressures on healthcare delivery as they require immediate diagnosis and treatment. The gl...

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Main Authors: Patricia M Kearney, Cathal O’Donnell, Johnny Aladkhen, Siobhán Masterson, Vera JC McCarthy, Edel Burton, Aine Merwick, Claire M Buckley
Format: Article
Language:English
Published: F1000 Research Ltd 2022-06-01
Series:HRB Open Research
Subjects:
Online Access:https://hrbopenresearch.org/articles/5-24/v2
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author Patricia M Kearney
Cathal O’Donnell
Johnny Aladkhen
Siobhán Masterson
Vera JC McCarthy
Edel Burton
Aine Merwick
Claire M Buckley
author_facet Patricia M Kearney
Cathal O’Donnell
Johnny Aladkhen
Siobhán Masterson
Vera JC McCarthy
Edel Burton
Aine Merwick
Claire M Buckley
author_sort Patricia M Kearney
collection DOAJ
description Background: The COVID-19 pandemic impacted on health service provision worldwide, including care for acute time sensitive conditions. Stroke and transient ischaemic attacks (TIA) are particularly vulnerable to pressures on healthcare delivery as they require immediate diagnosis and treatment. The global impact of the COVID-19 pandemic on prehospital emergency care for stroke/TIA is still largely unknown. Thus, the aim of this study is to conduct a systematic review and meta-analysis to investigate the impact of the COVID-19 pandemic on prehospital emergency care for stroke and TIA. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) guidelines, the review is registered on PROSPERO (registration number CRD42022315260). Peer-reviewed quantitative studies comparing prehospital emergency care for adults with stroke/TIA before and during the COVID-19 pandemic will be considered for inclusion. The outcomes of interest are ambulance times and emergency call volumes for stroke/TIA. A systematic search of databases including PubMed, Embase and Scopus will be conducted. Two authors will independently screen studies for inclusion based on predetermined inclusion and exclusion criteria. Data extraction and quality assessment will be conducted by two authors. Meta-analysis will be performed to calculate overall pooled estimates of ambulance times (primary outcome) and stroke/TIA call volumes (secondary outcome), where appropriate.  Where heterogeneity is low a fixed-effects model will be used and where heterogeneity is high a random-effects model will be used. Subgroup and sensitivity analyses will include location, stroke/TIA diagnosis and COVID-19 case numbers. Results: Data on primary and secondary outcomes will be provided. Results of subgroup/sensitivity analyses and quality assessment will also be presented. Conclusions: This review will identify existing evidence reporting the impact of the COVID-19 pandemic on prehospital emergency care for adult patients with stroke/TIA and provide summary estimates of effects on ambulance response times.
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spelling doaj.art-875156eae73b463691c6d04e58b131da2022-12-22T04:00:36ZengF1000 Research LtdHRB Open Research2515-48262022-06-01514835Effects of the COVID-19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack: A protocol for a systematic review and meta-analysis [version 2; peer review: 3 approved]Patricia M Kearney0https://orcid.org/0000-0001-9599-3540Cathal O’Donnell1Johnny Aladkhen2Siobhán Masterson3https://orcid.org/0000-0002-3003-4792Vera JC McCarthy4https://orcid.org/0000-0001-7573-7961Edel Burton5https://orcid.org/0000-0002-5847-0174Aine Merwick6Claire M Buckley7School of Public Health, University College Cork, Cork City, Cork, IrelandNational Ambulance Service, Health Service Executive, Dublin, IrelandSchool of Public Health, University College Cork, Cork City, Cork, IrelandNational Ambulance Service, Health Service Executive, Dublin, IrelandSchool of Nursing and Midwifery, University College Cork, Cork City, Cork, IrelandSchool of Public Health, University College Cork, Cork City, Cork, IrelandDepartment of Neurology, Cork University Hospital, Cork City, Cork, IrelandSchool of Public Health, University College Cork, Cork City, Cork, IrelandBackground: The COVID-19 pandemic impacted on health service provision worldwide, including care for acute time sensitive conditions. Stroke and transient ischaemic attacks (TIA) are particularly vulnerable to pressures on healthcare delivery as they require immediate diagnosis and treatment. The global impact of the COVID-19 pandemic on prehospital emergency care for stroke/TIA is still largely unknown. Thus, the aim of this study is to conduct a systematic review and meta-analysis to investigate the impact of the COVID-19 pandemic on prehospital emergency care for stroke and TIA. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta Analyses (PRISMA) guidelines, the review is registered on PROSPERO (registration number CRD42022315260). Peer-reviewed quantitative studies comparing prehospital emergency care for adults with stroke/TIA before and during the COVID-19 pandemic will be considered for inclusion. The outcomes of interest are ambulance times and emergency call volumes for stroke/TIA. A systematic search of databases including PubMed, Embase and Scopus will be conducted. Two authors will independently screen studies for inclusion based on predetermined inclusion and exclusion criteria. Data extraction and quality assessment will be conducted by two authors. Meta-analysis will be performed to calculate overall pooled estimates of ambulance times (primary outcome) and stroke/TIA call volumes (secondary outcome), where appropriate.  Where heterogeneity is low a fixed-effects model will be used and where heterogeneity is high a random-effects model will be used. Subgroup and sensitivity analyses will include location, stroke/TIA diagnosis and COVID-19 case numbers. Results: Data on primary and secondary outcomes will be provided. Results of subgroup/sensitivity analyses and quality assessment will also be presented. Conclusions: This review will identify existing evidence reporting the impact of the COVID-19 pandemic on prehospital emergency care for adult patients with stroke/TIA and provide summary estimates of effects on ambulance response times.https://hrbopenresearch.org/articles/5-24/v2Ambulance times; emergency care; COVID-19 pandemic; prehospital; protocol; stroke; systematic review; transient ischaemic attack.eng
spellingShingle Patricia M Kearney
Cathal O’Donnell
Johnny Aladkhen
Siobhán Masterson
Vera JC McCarthy
Edel Burton
Aine Merwick
Claire M Buckley
Effects of the COVID-19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack: A protocol for a systematic review and meta-analysis [version 2; peer review: 3 approved]
HRB Open Research
Ambulance times; emergency care; COVID-19 pandemic; prehospital; protocol; stroke; systematic review; transient ischaemic attack.
eng
title Effects of the COVID-19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack: A protocol for a systematic review and meta-analysis [version 2; peer review: 3 approved]
title_full Effects of the COVID-19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack: A protocol for a systematic review and meta-analysis [version 2; peer review: 3 approved]
title_fullStr Effects of the COVID-19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack: A protocol for a systematic review and meta-analysis [version 2; peer review: 3 approved]
title_full_unstemmed Effects of the COVID-19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack: A protocol for a systematic review and meta-analysis [version 2; peer review: 3 approved]
title_short Effects of the COVID-19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack: A protocol for a systematic review and meta-analysis [version 2; peer review: 3 approved]
title_sort effects of the covid 19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack a protocol for a systematic review and meta analysis version 2 peer review 3 approved
topic Ambulance times; emergency care; COVID-19 pandemic; prehospital; protocol; stroke; systematic review; transient ischaemic attack.
eng
url https://hrbopenresearch.org/articles/5-24/v2
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