Functionalized Mouth‐Conformable Interfaces for pH Evaluation of the Oral Cavity
Abstract Oral health monitoring is highly desired, especially for in home use, however, current methods are not sensitive enough and technically convoluted for this purpose. This paper presents incorporation of bioactive materials and colorimetric chemical sensors into routinely used oral appliances...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-06-01
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| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202003416 |
| _version_ | 1830133345649950720 |
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| author | Giusy Matzeu Gili R. S. Naveh Siddhart Agarwal Jeffery A. Roshko Nicholas A. Ostrovsky‐Snider Bradley S. Napier Fiorenzo G. Omenetto |
| author_facet | Giusy Matzeu Gili R. S. Naveh Siddhart Agarwal Jeffery A. Roshko Nicholas A. Ostrovsky‐Snider Bradley S. Napier Fiorenzo G. Omenetto |
| author_sort | Giusy Matzeu |
| collection | DOAJ |
| description | Abstract Oral health monitoring is highly desired, especially for in home use, however, current methods are not sensitive enough and technically convoluted for this purpose. This paper presents incorporation of bioactive materials and colorimetric chemical sensors into routinely used oral appliances transforming them into bioresponsive, conformable interfaces. Specifically, endodontic paper points and dental floss can be functionalized to locally sense and monitor pH variations within the oral cavity via color changes. Moreover, edible colorimetric indicators are developed and used to make sensing, edible devices in the form factor of candies that can dynamically and visually respond to acidity changes in saliva. These interfaces would enable early detection of caries (e.g., using dental floss and paper points) providing low‐cost point of care devices that respond in real‐time by detecting pH variations in biological fluids thus bringing monitoring to home settings . |
| first_indexed | 2024-12-17T06:51:39Z |
| format | Article |
| id | doaj.art-87542e4b26f3411ea290152eb8007de3 |
| institution | Directory Open Access Journal |
| issn | 2198-3844 |
| language | English |
| last_indexed | 2024-12-17T06:51:39Z |
| publishDate | 2021-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj.art-87542e4b26f3411ea290152eb8007de32022-12-21T21:59:35ZengWileyAdvanced Science2198-38442021-06-01812n/an/a10.1002/advs.202003416Functionalized Mouth‐Conformable Interfaces for pH Evaluation of the Oral CavityGiusy Matzeu0Gili R. S. Naveh1Siddhart Agarwal2Jeffery A. Roshko3Nicholas A. Ostrovsky‐Snider4Bradley S. Napier5Fiorenzo G. Omenetto6Silklab Department of Biomedical Engineering Tufts University Medford MA 02155 USAHarvard School of Dental Medicine 188 Longwood Avenue Boston MA 02115 USASilklab Department of Biomedical Engineering Tufts University Medford MA 02155 USASilklab Department of Biomedical Engineering Tufts University Medford MA 02155 USASilklab Department of Biomedical Engineering Tufts University Medford MA 02155 USASilklab Department of Biomedical Engineering Tufts University Medford MA 02155 USASilklab Department of Biomedical Engineering Tufts University Medford MA 02155 USAAbstract Oral health monitoring is highly desired, especially for in home use, however, current methods are not sensitive enough and technically convoluted for this purpose. This paper presents incorporation of bioactive materials and colorimetric chemical sensors into routinely used oral appliances transforming them into bioresponsive, conformable interfaces. Specifically, endodontic paper points and dental floss can be functionalized to locally sense and monitor pH variations within the oral cavity via color changes. Moreover, edible colorimetric indicators are developed and used to make sensing, edible devices in the form factor of candies that can dynamically and visually respond to acidity changes in saliva. These interfaces would enable early detection of caries (e.g., using dental floss and paper points) providing low‐cost point of care devices that respond in real‐time by detecting pH variations in biological fluids thus bringing monitoring to home settings .https://doi.org/10.1002/advs.202003416colorimetric sensorsmouth compatible interfacesoral cavity |
| spellingShingle | Giusy Matzeu Gili R. S. Naveh Siddhart Agarwal Jeffery A. Roshko Nicholas A. Ostrovsky‐Snider Bradley S. Napier Fiorenzo G. Omenetto Functionalized Mouth‐Conformable Interfaces for pH Evaluation of the Oral Cavity Advanced Science colorimetric sensors mouth compatible interfaces oral cavity |
| title | Functionalized Mouth‐Conformable Interfaces for pH Evaluation of the Oral Cavity |
| title_full | Functionalized Mouth‐Conformable Interfaces for pH Evaluation of the Oral Cavity |
| title_fullStr | Functionalized Mouth‐Conformable Interfaces for pH Evaluation of the Oral Cavity |
| title_full_unstemmed | Functionalized Mouth‐Conformable Interfaces for pH Evaluation of the Oral Cavity |
| title_short | Functionalized Mouth‐Conformable Interfaces for pH Evaluation of the Oral Cavity |
| title_sort | functionalized mouth conformable interfaces for ph evaluation of the oral cavity |
| topic | colorimetric sensors mouth compatible interfaces oral cavity |
| url | https://doi.org/10.1002/advs.202003416 |
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