Evolution of substrate specificity in a retained enzyme driven by gene loss
The connection between gene loss and the functional adaptation of retained proteins is still poorly understood. We apply phylogenomics and metabolic modeling to detect bacterial species that are evolving by gene loss, with the finding that Actinomycetaceae genomes from human cavities are undergoing...
Main Authors: | Ana Lilia Juárez-Vázquez, Janaka N Edirisinghe, Ernesto A Verduzco-Castro, Karolina Michalska, Chenggang Wu, Lianet Noda-García, Gyorgy Babnigg, Michael Endres, Sofía Medina-Ruíz, Julián Santoyo-Flores, Mauricio Carrillo-Tripp, Hung Ton-That, Andrzej Joachimiak, Christopher S Henry, Francisco Barona-Gómez |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-03-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/22679 |
Similar Items
-
Actinomyces neuii: a case report of a rare cause of acute infective endocarditis and literature review
by: Wei-Teng Yang, et al.
Published: (2019-06-01) -
Actinomyces neuii subsp. neuii Isolated from Perineal Abscess; Case Report
by: Emel AKBAŞ, et al.
Published: (2019-04-01) -
Antibacterial and cytotoxicity of chitosan nanocomposite loaded with thymol against some cariogenic bacteria
by: Matin Kordestani, et al.
Published: (2023-04-01) -
Comparison of Spatial Structures and Packaging of Phosphorybosil Pyrophosphate Synthetase 2 from <i>Thermus thermophilus</i> HB27 in Rhombohedral and Tetragonal Crystals
by: Yulia Abramchik, et al.
Published: (2021-09-01) -
Tandem riboswitches form a natural Boolean logic gate to control purine metabolism in bacteria
by: Madeline E Sherlock, et al.
Published: (2018-03-01)