The impact of driving pressure on postoperative pulmonary complication in patients with different respiratory spirometry
Abstract Risk factors for postoperative pulmonary complication (PPC) have not been determined according to preoperative respiratory spirometry. Thus, we aimed to find contributors for PPC in patients with restrictive or normal spirometric pattern. We analyzed 654 patients (379 with normal and 275 wi...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-24627-2 |
| _version_ | 1811190315363598336 |
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| author | Eun Jung Oh Bo-Guen Kim Sukhee Park Sangbin Han Beomsu Shin Hyun Lee Sun Hye Shin Jeayoun Kim Dancheong Choi Eun Ah Choi Hye Yun Park |
| author_facet | Eun Jung Oh Bo-Guen Kim Sukhee Park Sangbin Han Beomsu Shin Hyun Lee Sun Hye Shin Jeayoun Kim Dancheong Choi Eun Ah Choi Hye Yun Park |
| author_sort | Eun Jung Oh |
| collection | DOAJ |
| description | Abstract Risk factors for postoperative pulmonary complication (PPC) have not been determined according to preoperative respiratory spirometry. Thus, we aimed to find contributors for PPC in patients with restrictive or normal spirometric pattern. We analyzed 654 patients (379 with normal and 275 with restrictive spirometric pattern). PPCs comprised respiratory failure, pleural effusion, atelectasis, respiratory infection, and bronchospasm. We analyzed the association between perioperative factors and PPC using binary logistic regression. In particular, we conducted subgroup analysis on the patients stratified according to preoperative spirometry. Of 654 patients, 27/379 patients (7.1%) with normal spirometric pattern and 33/275 patients (12.0%) with restrictive spirometric pattern developed PPCs. Multivariable analysis demonstrated that high driving pressure was the only intraoperative modifiable factor increasing PPC risk (OR = 1.13 [1.02–1.25], p = 0.025). In the subgroup of patients with restrictive spirometric pattern, intraoperative driving pressure was significantly associated with PPC (OR = 1.21 [1.05–1.39], p = 0.009), whereas driving pressure was not associated with PPC in patients with normal spirometric pattern (OR = 1.04 [0.89–1.21], p = 0.639). In patients with restrictive spirometric pattern, greater intraoperative driving pressure is significantly associated with increased PPC risk. In contrast, intraoperative driving pressure is not associated with PPC in patients with normal spirometric pattern. |
| first_indexed | 2024-04-11T14:48:14Z |
| format | Article |
| id | doaj.art-8758a85cf86e45c4b5be00bf67822154 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-11T14:48:14Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-8758a85cf86e45c4b5be00bf678221542022-12-22T04:17:33ZengNature PortfolioScientific Reports2045-23222022-12-011211910.1038/s41598-022-24627-2The impact of driving pressure on postoperative pulmonary complication in patients with different respiratory spirometryEun Jung Oh0Bo-Guen Kim1Sukhee Park2Sangbin Han3Beomsu Shin4Hyun Lee5Sun Hye Shin6Jeayoun Kim7Dancheong Choi8Eun Ah Choi9Hye Yun Park10Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, International St. Mary’s Hospital, Catholic Kwandong University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Medicine, Yonsei University Wonju College of MedicineDepartment of Internal Medicine, Hanyang Medical Center, Hanyang University College of MedicineDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineAbstract Risk factors for postoperative pulmonary complication (PPC) have not been determined according to preoperative respiratory spirometry. Thus, we aimed to find contributors for PPC in patients with restrictive or normal spirometric pattern. We analyzed 654 patients (379 with normal and 275 with restrictive spirometric pattern). PPCs comprised respiratory failure, pleural effusion, atelectasis, respiratory infection, and bronchospasm. We analyzed the association between perioperative factors and PPC using binary logistic regression. In particular, we conducted subgroup analysis on the patients stratified according to preoperative spirometry. Of 654 patients, 27/379 patients (7.1%) with normal spirometric pattern and 33/275 patients (12.0%) with restrictive spirometric pattern developed PPCs. Multivariable analysis demonstrated that high driving pressure was the only intraoperative modifiable factor increasing PPC risk (OR = 1.13 [1.02–1.25], p = 0.025). In the subgroup of patients with restrictive spirometric pattern, intraoperative driving pressure was significantly associated with PPC (OR = 1.21 [1.05–1.39], p = 0.009), whereas driving pressure was not associated with PPC in patients with normal spirometric pattern (OR = 1.04 [0.89–1.21], p = 0.639). In patients with restrictive spirometric pattern, greater intraoperative driving pressure is significantly associated with increased PPC risk. In contrast, intraoperative driving pressure is not associated with PPC in patients with normal spirometric pattern.https://doi.org/10.1038/s41598-022-24627-2 |
| spellingShingle | Eun Jung Oh Bo-Guen Kim Sukhee Park Sangbin Han Beomsu Shin Hyun Lee Sun Hye Shin Jeayoun Kim Dancheong Choi Eun Ah Choi Hye Yun Park The impact of driving pressure on postoperative pulmonary complication in patients with different respiratory spirometry Scientific Reports |
| title | The impact of driving pressure on postoperative pulmonary complication in patients with different respiratory spirometry |
| title_full | The impact of driving pressure on postoperative pulmonary complication in patients with different respiratory spirometry |
| title_fullStr | The impact of driving pressure on postoperative pulmonary complication in patients with different respiratory spirometry |
| title_full_unstemmed | The impact of driving pressure on postoperative pulmonary complication in patients with different respiratory spirometry |
| title_short | The impact of driving pressure on postoperative pulmonary complication in patients with different respiratory spirometry |
| title_sort | impact of driving pressure on postoperative pulmonary complication in patients with different respiratory spirometry |
| url | https://doi.org/10.1038/s41598-022-24627-2 |
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