In Vivo Acquisition of Carbapenemase Gene blaKPC-2 in Multiple Species of Enterobacteriaceae through Horizontal Transfer of Insertion Sequence or Plasmid

In Vivo Acquisition of Carbapenemase Gene blaKPC-2 in Multiple Species of Enterobacteriaceae through Horizontal Transfer of Insertion Sequence or Plasmid

Objectives: Current worldwide spread of carbapenem resistance in Enterobacteriaceae constitutes a critical public health threat. This study aims to investigate how carbapenem resistance is acquired in Enterobacteriaceae in patients during antimicrobial therapy. Methods: Clinical strains from the sam...

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Bibliographic Details
Main Authors: Baixing Ding, Zhen Shen, Fupin Hu, Meiping Ye, Xiaogang Xu, Qinglan Guo, Minggui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Microbiology
Subjects:
Enterobacteriaceae
insertion sequence
Plasmid
Carbapenem resistance
KPC-2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01651/full

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