The Anti-tumoral Effect of β-D-Mannuronic Acid (M2000) as a Novel NSAID on Treg Cells Frequency and MMP-2, MMP-9, CCL22 and TGFβ1 Gene Expression in Pre-surgical Breast Cancer Patients

The Anti-tumoral Effect of β-D-Mannuronic Acid (M2000) as a Novel NSAID on Treg Cells Frequency and MMP-2, MMP-9, CCL22 and TGFβ1 Gene Expression in Pre-surgical Breast Cancer Patients

With respect to the role of chronic inflammation in the induction and progression of breast cancer (BC). The relationship between tumor and tumor microenvironment may be a hopeful strategy for BC therapy. According to the effect of β-D-Mannuronic acid (M2000) as a novel non-steroidal anti-inflammato...

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Bibliographic Details
Main Authors: Sarvenaz Kashefi, Hamid Ahmadi, Ramesh Omranipour, Habibollah Mahmoodzadeh, Fahimeh Jafarnezhad-Ansariha, Farzaneh Tofighi Zavareh, Abbas Mirshafiey
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-02-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Breast Cancer
β-D-Mannuronic acid
Chemopreventive
M2000
Non-steroidal anti-inflammatory drug
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2157

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