Long-term survival with repeat resection for lung oligometastasis from pancreatic ductal adenocarcinoma: a case report
Abstract Background Long-term survival after resection of metastases from pancreatic ductal adenocarcinoma is rare. Case presentation A 54-year-old man underwent pancreaticoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDAC) with UICC staging pT3N1M0 followed by adjuvant chemotherapy with...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2018-03-01
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| Series: | Surgical Case Reports |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40792-018-0435-2 |
| _version_ | 1818385308620685312 |
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| author | Ryota Matsuki Masanori Sugiyama Hidefumi Takei Haruhiko Kondo Masachika Fujiwara Junji Shibahara Junji Furuse |
| author_facet | Ryota Matsuki Masanori Sugiyama Hidefumi Takei Haruhiko Kondo Masachika Fujiwara Junji Shibahara Junji Furuse |
| author_sort | Ryota Matsuki |
| collection | DOAJ |
| description | Abstract Background Long-term survival after resection of metastases from pancreatic ductal adenocarcinoma is rare. Case presentation A 54-year-old man underwent pancreaticoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDAC) with UICC staging pT3N1M0 followed by adjuvant chemotherapy with gemcitabine (GEM). Three years after radical resection of the primary tumor, a tiny nodule was found in the lower lobe of the left lung. Despite treatment with GEM, it increased gradually, but no other metastases were found. Eighteen months after the first indication of the nodule, wedge resection was performed. Pathological examination of the nodule indicated a metastatic tumor from PDAC. Pulmonary metastasectomy was again performed for lung oligometastases at 77 and 101 months after PD. The patient has been asymptomatic without tumor recurrence for 4 years since the last pulmonary resection. Conclusions In PDAC, the treatment strategy for oligometastasis is controversial. However, a few cases of long-term survival after pulmonary metastasectomy for oligometastasis of PDAC have been reported. More such cases need to be studied to address this issue effectively. |
| first_indexed | 2024-12-14T03:36:06Z |
| format | Article |
| id | doaj.art-8760a350f9ae411595c93a2dcb60dafc |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-12-14T03:36:06Z |
| publishDate | 2018-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-8760a350f9ae411595c93a2dcb60dafc2022-12-21T23:18:37ZengSpringerOpenSurgical Case Reports2198-77932018-03-01411510.1186/s40792-018-0435-2Long-term survival with repeat resection for lung oligometastasis from pancreatic ductal adenocarcinoma: a case reportRyota Matsuki0Masanori Sugiyama1Hidefumi Takei2Haruhiko Kondo3Masachika Fujiwara4Junji Shibahara5Junji Furuse6Department of Surgery, School of Medicine, Kyorin UniversityDepartment of Surgery, School of Medicine, Kyorin UniversityDepartment of General Thoracic Surgery, School of Medicine, Kyorin UniversityDepartment of General Thoracic Surgery, School of Medicine, Kyorin UniversityDepartment of Pathology, School of Medicine, Kyorin UniversityDepartment of Pathology, School of Medicine, Kyorin UniversityDepartment of Medical Oncology, School of Medicine, Kyorin UniversityAbstract Background Long-term survival after resection of metastases from pancreatic ductal adenocarcinoma is rare. Case presentation A 54-year-old man underwent pancreaticoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDAC) with UICC staging pT3N1M0 followed by adjuvant chemotherapy with gemcitabine (GEM). Three years after radical resection of the primary tumor, a tiny nodule was found in the lower lobe of the left lung. Despite treatment with GEM, it increased gradually, but no other metastases were found. Eighteen months after the first indication of the nodule, wedge resection was performed. Pathological examination of the nodule indicated a metastatic tumor from PDAC. Pulmonary metastasectomy was again performed for lung oligometastases at 77 and 101 months after PD. The patient has been asymptomatic without tumor recurrence for 4 years since the last pulmonary resection. Conclusions In PDAC, the treatment strategy for oligometastasis is controversial. However, a few cases of long-term survival after pulmonary metastasectomy for oligometastasis of PDAC have been reported. More such cases need to be studied to address this issue effectively.http://link.springer.com/article/10.1186/s40792-018-0435-2Pancreatic ductal adenocarcinomaOligometastasisPulmonary metastasectomy |
| spellingShingle | Ryota Matsuki Masanori Sugiyama Hidefumi Takei Haruhiko Kondo Masachika Fujiwara Junji Shibahara Junji Furuse Long-term survival with repeat resection for lung oligometastasis from pancreatic ductal adenocarcinoma: a case report Surgical Case Reports Pancreatic ductal adenocarcinoma Oligometastasis Pulmonary metastasectomy |
| title | Long-term survival with repeat resection for lung oligometastasis from pancreatic ductal adenocarcinoma: a case report |
| title_full | Long-term survival with repeat resection for lung oligometastasis from pancreatic ductal adenocarcinoma: a case report |
| title_fullStr | Long-term survival with repeat resection for lung oligometastasis from pancreatic ductal adenocarcinoma: a case report |
| title_full_unstemmed | Long-term survival with repeat resection for lung oligometastasis from pancreatic ductal adenocarcinoma: a case report |
| title_short | Long-term survival with repeat resection for lung oligometastasis from pancreatic ductal adenocarcinoma: a case report |
| title_sort | long term survival with repeat resection for lung oligometastasis from pancreatic ductal adenocarcinoma a case report |
| topic | Pancreatic ductal adenocarcinoma Oligometastasis Pulmonary metastasectomy |
| url | http://link.springer.com/article/10.1186/s40792-018-0435-2 |
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