Statins Inhibit the Gliosis of MIO-M1, a Müller Glial Cell Line Induced by TRPV4 Activation

Statins Inhibit the Gliosis of MIO-M1, a Müller Glial Cell Line Induced by TRPV4 Activation

We characterized Müller cell gliosis induced by the activation of transient receptor potential vanilloid-type 4 (TRPV4) and assessed whether statins could modulate the gliosis. The human Müller cell line, MIO-M1, was used to analyze the gliosis caused by glaucomatous stimulation. To induce Müller gl...

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Bibliographic Details
Main Authors: Youn Hye Jo, Go Woon Choi, Mi-Lyang Kim, Kyung Rim Sung
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
glaucoma
Müller gliosis
NF-κB pathway
statin
TNF-α
Online Access:https://www.mdpi.com/1422-0067/23/9/5190

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