The role of TLR4/MyD88/NF-κB in the protective effect of ulinastatin on the intestinal mucosal barrier in mice with sepsis

The role of TLR4/MyD88/NF-κB in the protective effect of ulinastatin on the intestinal mucosal barrier in mice with sepsis

Abstract Objective To investigate the effect of the TLR4/MyD88/NF-κB (Toll-like receptor 4/myeloid differentiation factor/nuclear factor kappa B) signalling pathway on the protective effect of ulinastatin on the intestinal mucosal barrier in mice with sepsis. Methods A mouse model of sepsis was esta...

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Bibliographic Details
Main Authors: Song Wenying, Huang Jing, Li Ying, Ding Hui
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Anesthesiology
Subjects:
Sepsis
Ulinastatin
TLR4
Online Access:https://doi.org/10.1186/s12871-023-02374-9

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