Cell Plasticity and Prostate Cancer: The Role of Epithelial–Mesenchymal Transition in Tumor Progression, Invasion, Metastasis and Cancer Therapy Resistance

Cell Plasticity and Prostate Cancer: The Role of Epithelial–Mesenchymal Transition in Tumor Progression, Invasion, Metastasis and Cancer Therapy Resistance

Prostate cancer, the second most common malignancy in men, is characterized by high heterogeneity that poses several therapeutic challenges. Epithelial–mesenchymal transition (EMT) is a dynamic, reversible cellular process which is essential in normal embryonic morphogenesis and wound healing. Howev...

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Bibliographic Details
Main Authors: Sofia Papanikolaou, Aikaterini Vourda, Spyros Syggelos, Kostis Gyftopoulos
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
prostate cancer
EMT
metastasis
cell plasticity
therapy resistance
Online Access:https://www.mdpi.com/2072-6694/13/11/2795

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