Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition

Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition

We previously showed that Fmo5−/− mice exhibit a lean phenotype and slower metabolic ageing. Their characteristics include lower plasma glucose and cholesterol, greater glucose tolerance and insulin sensitivity, and a reduction in age-related weight gain and whole-body fat deposition. In this paper,...

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Bibliographic Details
Main Authors: Sunil Veeravalli, Dorsa Varshavi, Flora H. Scott, Dorna Varshavi, Frank S. Pullen, Kirill Veselkov, Ian R. Phillips, Jeremy R. Everett, Elizabeth A. Shephard
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Physiology
Subjects:
antibiotic
fecal transplant
gut microbiome
metabolite
NMR
stomach
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.859681/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.859681/full

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