Current understanding of macrophages in intracranial aneurysm: relevant etiological manifestations, signaling modulation and therapeutic strategies

Current understanding of macrophages in intracranial aneurysm: relevant etiological manifestations, signaling modulation and therapeutic strategies

Macrophages activation and inflammatory response play crucial roles in intracranial aneurysm (IA) formation and progression. The outcome of ruptured IA is considerably poor, and the mechanisms that trigger IA progression and rupture remain to be clarified, thereby developing effective therapy to pre...

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Bibliographic Details
Main Authors: Jian Duan, Qijie Zhao, Zeyuan He, Shuang Tang, Jia Duan, Wenli Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
intracranial aneurysm (IA)
macrophages
inflammation
cellular signaling
therapeutic strategy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1320098/full

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