Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study
Abstract Background Eclampsia, considered as serious complication of preeclampsia, remains a life-threatening condition among pregnant women. It accounts for 12% of maternal deaths and 16–31% of perinatal deaths worldwide. Most deaths from eclampsia occurred in resource-limited settings of sub-Sahar...
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BMC
2021-06-01
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Series: | BMC Pregnancy and Childbirth |
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Online Access: | https://doi.org/10.1186/s12884-021-03875-6 |
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author | Koech Irene Poli Philippe Amubuomombe Richard Mogeni Cheruiyot Andrew Ann Mwangi Orang’o Elkanah Omenge |
author_facet | Koech Irene Poli Philippe Amubuomombe Richard Mogeni Cheruiyot Andrew Ann Mwangi Orang’o Elkanah Omenge |
author_sort | Koech Irene |
collection | DOAJ |
description | Abstract Background Eclampsia, considered as serious complication of preeclampsia, remains a life-threatening condition among pregnant women. It accounts for 12% of maternal deaths and 16–31% of perinatal deaths worldwide. Most deaths from eclampsia occurred in resource-limited settings of sub-Saharan Africa. This study was performed to determine the optimum mode of delivery, as well as factors associated with the mode of delivery, in women admitted with eclampsia at Riley Mother and Baby Hospital. Methods This was a hospital-based longitudinal case-series study conducted at the largest and busiest obstetric unit of the tertiary hospital of western Kenya. Maternal and perinatal variables, such as age, parity, medications, initiation of labour, mode of delivery, admission to the intensive care unit, admission to the newborn care unit, organ injuries, and mortality, were analysed using the Statistical Package for the Social Sciences software version 20.0. Quantitative data were described using frequencies and percentages. The significance of the obtained results was judged at the 5% level. The chi-square test was used for categorical variables, and Fisher’s exact test or the Monte Carlo correction was used for correction of the chi-square test when more than 20% of the cells had an expected count of less than 5. Results During the study period, 53 patients diagnosed with eclampsia were treated and followed up to 6 weeks postpartum. There was zero maternal mortality; however, perinatal mortality was reported in 9.4%. Parity was statistically associated with an increased odds of adverse perinatal outcomes (p = 0.004, OR = 9.1, 95% CI = 2.0–40.8) and caesarean delivery (p = 0.020, OR = 4.7, 95% CI = 1.3–17.1). In addition, the induction of labour decreased the risk of adverse outcomes (p = 0.232, OR = 0.3, 95% CI = 0.1–2.0). Conclusion There is no benefit of emergency caesarean section for women with eclampsia. This study showed that induction of labour and vaginal delivery can be successfully achieved in pregnant women with eclampsia. Maternal and perinatal mortality from eclampsia can be prevented through prompt and effective care. |
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issn | 1471-2393 |
language | English |
last_indexed | 2024-12-16T18:41:40Z |
publishDate | 2021-06-01 |
publisher | BMC |
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spelling | doaj.art-8773de5120d942e6aba450e2bcca78532022-12-21T22:21:02ZengBMCBMC Pregnancy and Childbirth1471-23932021-06-0121111410.1186/s12884-021-03875-6Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series studyKoech Irene0Poli Philippe Amubuomombe1Richard Mogeni2Cheruiyot Andrew3Ann Mwangi4Orang’o Elkanah Omenge5Reproductive Health, Moi Teaching& Referral HospitalReproductive Health, Moi Teaching& Referral HospitalReproductive Health, Moi Teaching& Referral HospitalDepartment of Reproductive Health, Moi University School of MedicineDepartment of Behavioural Sciences, Moi University School of MedicineReproductive Health, Moi Teaching& Referral HospitalAbstract Background Eclampsia, considered as serious complication of preeclampsia, remains a life-threatening condition among pregnant women. It accounts for 12% of maternal deaths and 16–31% of perinatal deaths worldwide. Most deaths from eclampsia occurred in resource-limited settings of sub-Saharan Africa. This study was performed to determine the optimum mode of delivery, as well as factors associated with the mode of delivery, in women admitted with eclampsia at Riley Mother and Baby Hospital. Methods This was a hospital-based longitudinal case-series study conducted at the largest and busiest obstetric unit of the tertiary hospital of western Kenya. Maternal and perinatal variables, such as age, parity, medications, initiation of labour, mode of delivery, admission to the intensive care unit, admission to the newborn care unit, organ injuries, and mortality, were analysed using the Statistical Package for the Social Sciences software version 20.0. Quantitative data were described using frequencies and percentages. The significance of the obtained results was judged at the 5% level. The chi-square test was used for categorical variables, and Fisher’s exact test or the Monte Carlo correction was used for correction of the chi-square test when more than 20% of the cells had an expected count of less than 5. Results During the study period, 53 patients diagnosed with eclampsia were treated and followed up to 6 weeks postpartum. There was zero maternal mortality; however, perinatal mortality was reported in 9.4%. Parity was statistically associated with an increased odds of adverse perinatal outcomes (p = 0.004, OR = 9.1, 95% CI = 2.0–40.8) and caesarean delivery (p = 0.020, OR = 4.7, 95% CI = 1.3–17.1). In addition, the induction of labour decreased the risk of adverse outcomes (p = 0.232, OR = 0.3, 95% CI = 0.1–2.0). Conclusion There is no benefit of emergency caesarean section for women with eclampsia. This study showed that induction of labour and vaginal delivery can be successfully achieved in pregnant women with eclampsia. Maternal and perinatal mortality from eclampsia can be prevented through prompt and effective care.https://doi.org/10.1186/s12884-021-03875-6Maternal and perinatal outcomesEclampsiaMode of deliveryResource-limited settings |
spellingShingle | Koech Irene Poli Philippe Amubuomombe Richard Mogeni Cheruiyot Andrew Ann Mwangi Orang’o Elkanah Omenge Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study BMC Pregnancy and Childbirth Maternal and perinatal outcomes Eclampsia Mode of delivery Resource-limited settings |
title | Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study |
title_full | Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study |
title_fullStr | Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study |
title_full_unstemmed | Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study |
title_short | Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study |
title_sort | maternal and perinatal outcomes in women with eclampsia by mode of delivery at riley mother baby hospital a longitudinal case series study |
topic | Maternal and perinatal outcomes Eclampsia Mode of delivery Resource-limited settings |
url | https://doi.org/10.1186/s12884-021-03875-6 |
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