Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study

Abstract Background Eclampsia, considered as serious complication of preeclampsia, remains a life-threatening condition among pregnant women. It accounts for 12% of maternal deaths and 16–31% of perinatal deaths worldwide. Most deaths from eclampsia occurred in resource-limited settings of sub-Sahar...

Full description

Bibliographic Details
Main Authors: Koech Irene, Poli Philippe Amubuomombe, Richard Mogeni, Cheruiyot Andrew, Ann Mwangi, Orang’o Elkanah Omenge
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Pregnancy and Childbirth
Subjects:
Online Access:https://doi.org/10.1186/s12884-021-03875-6
_version_ 1818623476221607936
author Koech Irene
Poli Philippe Amubuomombe
Richard Mogeni
Cheruiyot Andrew
Ann Mwangi
Orang’o Elkanah Omenge
author_facet Koech Irene
Poli Philippe Amubuomombe
Richard Mogeni
Cheruiyot Andrew
Ann Mwangi
Orang’o Elkanah Omenge
author_sort Koech Irene
collection DOAJ
description Abstract Background Eclampsia, considered as serious complication of preeclampsia, remains a life-threatening condition among pregnant women. It accounts for 12% of maternal deaths and 16–31% of perinatal deaths worldwide. Most deaths from eclampsia occurred in resource-limited settings of sub-Saharan Africa. This study was performed to determine the optimum mode of delivery, as well as factors associated with the mode of delivery, in women admitted with eclampsia at Riley Mother and Baby Hospital. Methods This was a hospital-based longitudinal case-series study conducted at the largest and busiest obstetric unit of the tertiary hospital of western Kenya. Maternal and perinatal variables, such as age, parity, medications, initiation of labour, mode of delivery, admission to the intensive care unit, admission to the newborn care unit, organ injuries, and mortality, were analysed using the Statistical Package for the Social Sciences software version 20.0. Quantitative data were described using frequencies and percentages. The significance of the obtained results was judged at the 5% level. The chi-square test was used for categorical variables, and Fisher’s exact test or the Monte Carlo correction was used for correction of the chi-square test when more than 20% of the cells had an expected count of less than 5. Results During the study period, 53 patients diagnosed with eclampsia were treated and followed up to 6 weeks postpartum. There was zero maternal mortality; however, perinatal mortality was reported in 9.4%. Parity was statistically associated with an increased odds of adverse perinatal outcomes (p = 0.004, OR = 9.1, 95% CI = 2.0–40.8) and caesarean delivery (p = 0.020, OR = 4.7, 95% CI = 1.3–17.1). In addition, the induction of labour decreased the risk of adverse outcomes (p = 0.232, OR = 0.3, 95% CI = 0.1–2.0). Conclusion There is no benefit of emergency caesarean section for women with eclampsia. This study showed that induction of labour and vaginal delivery can be successfully achieved in pregnant women with eclampsia. Maternal and perinatal mortality from eclampsia can be prevented through prompt and effective care.
first_indexed 2024-12-16T18:41:40Z
format Article
id doaj.art-8773de5120d942e6aba450e2bcca7853
institution Directory Open Access Journal
issn 1471-2393
language English
last_indexed 2024-12-16T18:41:40Z
publishDate 2021-06-01
publisher BMC
record_format Article
series BMC Pregnancy and Childbirth
spelling doaj.art-8773de5120d942e6aba450e2bcca78532022-12-21T22:21:02ZengBMCBMC Pregnancy and Childbirth1471-23932021-06-0121111410.1186/s12884-021-03875-6Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series studyKoech Irene0Poli Philippe Amubuomombe1Richard Mogeni2Cheruiyot Andrew3Ann Mwangi4Orang’o Elkanah Omenge5Reproductive Health, Moi Teaching& Referral HospitalReproductive Health, Moi Teaching& Referral HospitalReproductive Health, Moi Teaching& Referral HospitalDepartment of Reproductive Health, Moi University School of MedicineDepartment of Behavioural Sciences, Moi University School of MedicineReproductive Health, Moi Teaching& Referral HospitalAbstract Background Eclampsia, considered as serious complication of preeclampsia, remains a life-threatening condition among pregnant women. It accounts for 12% of maternal deaths and 16–31% of perinatal deaths worldwide. Most deaths from eclampsia occurred in resource-limited settings of sub-Saharan Africa. This study was performed to determine the optimum mode of delivery, as well as factors associated with the mode of delivery, in women admitted with eclampsia at Riley Mother and Baby Hospital. Methods This was a hospital-based longitudinal case-series study conducted at the largest and busiest obstetric unit of the tertiary hospital of western Kenya. Maternal and perinatal variables, such as age, parity, medications, initiation of labour, mode of delivery, admission to the intensive care unit, admission to the newborn care unit, organ injuries, and mortality, were analysed using the Statistical Package for the Social Sciences software version 20.0. Quantitative data were described using frequencies and percentages. The significance of the obtained results was judged at the 5% level. The chi-square test was used for categorical variables, and Fisher’s exact test or the Monte Carlo correction was used for correction of the chi-square test when more than 20% of the cells had an expected count of less than 5. Results During the study period, 53 patients diagnosed with eclampsia were treated and followed up to 6 weeks postpartum. There was zero maternal mortality; however, perinatal mortality was reported in 9.4%. Parity was statistically associated with an increased odds of adverse perinatal outcomes (p = 0.004, OR = 9.1, 95% CI = 2.0–40.8) and caesarean delivery (p = 0.020, OR = 4.7, 95% CI = 1.3–17.1). In addition, the induction of labour decreased the risk of adverse outcomes (p = 0.232, OR = 0.3, 95% CI = 0.1–2.0). Conclusion There is no benefit of emergency caesarean section for women with eclampsia. This study showed that induction of labour and vaginal delivery can be successfully achieved in pregnant women with eclampsia. Maternal and perinatal mortality from eclampsia can be prevented through prompt and effective care.https://doi.org/10.1186/s12884-021-03875-6Maternal and perinatal outcomesEclampsiaMode of deliveryResource-limited settings
spellingShingle Koech Irene
Poli Philippe Amubuomombe
Richard Mogeni
Cheruiyot Andrew
Ann Mwangi
Orang’o Elkanah Omenge
Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study
BMC Pregnancy and Childbirth
Maternal and perinatal outcomes
Eclampsia
Mode of delivery
Resource-limited settings
title Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study
title_full Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study
title_fullStr Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study
title_full_unstemmed Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study
title_short Maternal and perinatal outcomes in women with eclampsia by mode of delivery at Riley mother baby hospital: a longitudinal case-series study
title_sort maternal and perinatal outcomes in women with eclampsia by mode of delivery at riley mother baby hospital a longitudinal case series study
topic Maternal and perinatal outcomes
Eclampsia
Mode of delivery
Resource-limited settings
url https://doi.org/10.1186/s12884-021-03875-6
work_keys_str_mv AT koechirene maternalandperinataloutcomesinwomenwitheclampsiabymodeofdeliveryatrileymotherbabyhospitalalongitudinalcaseseriesstudy
AT poliphilippeamubuomombe maternalandperinataloutcomesinwomenwitheclampsiabymodeofdeliveryatrileymotherbabyhospitalalongitudinalcaseseriesstudy
AT richardmogeni maternalandperinataloutcomesinwomenwitheclampsiabymodeofdeliveryatrileymotherbabyhospitalalongitudinalcaseseriesstudy
AT cheruiyotandrew maternalandperinataloutcomesinwomenwitheclampsiabymodeofdeliveryatrileymotherbabyhospitalalongitudinalcaseseriesstudy
AT annmwangi maternalandperinataloutcomesinwomenwitheclampsiabymodeofdeliveryatrileymotherbabyhospitalalongitudinalcaseseriesstudy
AT orangoelkanahomenge maternalandperinataloutcomesinwomenwitheclampsiabymodeofdeliveryatrileymotherbabyhospitalalongitudinalcaseseriesstudy