Management of Endodontic and Periodontal Lesions: the Role of Regenerative Dentistry and Biomaterials

Regenerative dentistry represents a novel interdisciplinary approach involving biomaterials, several molecules and mesenchymal stem cells (MSCs), preferably derived from oral tissues. The pivotal role of MSCs depends on the fact that they can differentiate into different cell lineages and have the s...

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Main Authors: Marco Tatullo, Francesco Riccitiello, Sandro Rengo, Benedetta Marrelli, Rosa Valletta, Gianrico Spagnuolo
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Dentistry Journal
Subjects:
Online Access:https://www.mdpi.com/2304-6767/8/2/32
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author Marco Tatullo
Francesco Riccitiello
Sandro Rengo
Benedetta Marrelli
Rosa Valletta
Gianrico Spagnuolo
author_facet Marco Tatullo
Francesco Riccitiello
Sandro Rengo
Benedetta Marrelli
Rosa Valletta
Gianrico Spagnuolo
author_sort Marco Tatullo
collection DOAJ
description Regenerative dentistry represents a novel interdisciplinary approach involving biomaterials, several molecules and mesenchymal stem cells (MSCs), preferably derived from oral tissues. The pivotal role of MSCs depends on the fact that they can differentiate into different cell lineages and have the strategic role to release bioactive substances that stimulate the renewal and regeneration of damaged tissues. The role of regenerative dentistry is promising in all the branches of dentistry: the most intriguing application is related to the management of endodontic and periodontal defects, overcoming the surgical approach and the implantology as a consequence of a poorly efficient therapeutic plan.
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spelling doaj.art-87778ad13a854c92a74275080ad2a7052023-11-19T20:36:11ZengMDPI AGDentistry Journal2304-67672020-04-01823210.3390/dj8020032Management of Endodontic and Periodontal Lesions: the Role of Regenerative Dentistry and BiomaterialsMarco Tatullo0Francesco Riccitiello1Sandro Rengo2Benedetta Marrelli3Rosa Valletta4Gianrico Spagnuolo5Department of Medical Sciences, Neurosciences and Sense Organs, University of Bari, 70124 Bari, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Napoli Federico II, 80131 Naples, ItalyDepartment of Health Sciences, Magna Graecia University of Catanzaro, 88100 Catanzaro, ItalyMarrelli Health-Healthcare Center, St. Enrico Fermi, 88900 Crotone, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Napoli Federico II, 80131 Naples, ItalyDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Napoli Federico II, 80131 Naples, ItalyRegenerative dentistry represents a novel interdisciplinary approach involving biomaterials, several molecules and mesenchymal stem cells (MSCs), preferably derived from oral tissues. The pivotal role of MSCs depends on the fact that they can differentiate into different cell lineages and have the strategic role to release bioactive substances that stimulate the renewal and regeneration of damaged tissues. The role of regenerative dentistry is promising in all the branches of dentistry: the most intriguing application is related to the management of endodontic and periodontal defects, overcoming the surgical approach and the implantology as a consequence of a poorly efficient therapeutic plan.https://www.mdpi.com/2304-6767/8/2/32regenerative dentistrydental stem cellsbiomaterialsdental materialstissue engineeringtranslational medicine
spellingShingle Marco Tatullo
Francesco Riccitiello
Sandro Rengo
Benedetta Marrelli
Rosa Valletta
Gianrico Spagnuolo
Management of Endodontic and Periodontal Lesions: the Role of Regenerative Dentistry and Biomaterials
Dentistry Journal
regenerative dentistry
dental stem cells
biomaterials
dental materials
tissue engineering
translational medicine
title Management of Endodontic and Periodontal Lesions: the Role of Regenerative Dentistry and Biomaterials
title_full Management of Endodontic and Periodontal Lesions: the Role of Regenerative Dentistry and Biomaterials
title_fullStr Management of Endodontic and Periodontal Lesions: the Role of Regenerative Dentistry and Biomaterials
title_full_unstemmed Management of Endodontic and Periodontal Lesions: the Role of Regenerative Dentistry and Biomaterials
title_short Management of Endodontic and Periodontal Lesions: the Role of Regenerative Dentistry and Biomaterials
title_sort management of endodontic and periodontal lesions the role of regenerative dentistry and biomaterials
topic regenerative dentistry
dental stem cells
biomaterials
dental materials
tissue engineering
translational medicine
url https://www.mdpi.com/2304-6767/8/2/32
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