Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction

Low frequency (≤ 1 Hz) repetitive transcranial magnetic stimulation (rTMS) can affect the excitability of the cerebral cortex and synaptic plasticity. Although this is a common method for clinical treatment of cerebral infarction, whether it promotes the recovery of motor function remains controvers...

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Main Authors: Zhi-yong Meng, Wei-qun Song
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=4;spage=610;epage=613;aulast=Meng
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author Zhi-yong Meng
Wei-qun Song
author_facet Zhi-yong Meng
Wei-qun Song
author_sort Zhi-yong Meng
collection DOAJ
description Low frequency (≤ 1 Hz) repetitive transcranial magnetic stimulation (rTMS) can affect the excitability of the cerebral cortex and synaptic plasticity. Although this is a common method for clinical treatment of cerebral infarction, whether it promotes the recovery of motor function remains controversial. Twenty patients with cerebral infarction combined with hemiparalysis were equally and randomly divided into a low frequency rTMS group and a control group. The patients in the low frequency rTMS group were given 1-Hz rTMS to the contralateral primary motor cortex with a stimulus intensity of 90% motor threshold, 30 minutes/day. The patients in the control group were given sham stimulation. After 14 days of treatment, clinical function scores (National Institute of Health Stroke Scale, Barthel Index, and Fugl-Meyer Assessment) improved significantly in the low frequency rTMS group, and the effects were better than that in the control group. We conclude that low frequency (1 Hz) rTMS for 14 days can help improve motor function after cerebral infarction.
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spelling doaj.art-877b3a651fdb4b8883d82837e2c46d502022-12-21T23:07:48ZengWolters Kluwer Medknow PublicationsNeural Regeneration Research1673-53742017-01-0112461061310.4103/1673-5374.205100Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarctionZhi-yong MengWei-qun SongLow frequency (≤ 1 Hz) repetitive transcranial magnetic stimulation (rTMS) can affect the excitability of the cerebral cortex and synaptic plasticity. Although this is a common method for clinical treatment of cerebral infarction, whether it promotes the recovery of motor function remains controversial. Twenty patients with cerebral infarction combined with hemiparalysis were equally and randomly divided into a low frequency rTMS group and a control group. The patients in the low frequency rTMS group were given 1-Hz rTMS to the contralateral primary motor cortex with a stimulus intensity of 90% motor threshold, 30 minutes/day. The patients in the control group were given sham stimulation. After 14 days of treatment, clinical function scores (National Institute of Health Stroke Scale, Barthel Index, and Fugl-Meyer Assessment) improved significantly in the low frequency rTMS group, and the effects were better than that in the control group. We conclude that low frequency (1 Hz) rTMS for 14 days can help improve motor function after cerebral infarction.http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=4;spage=610;epage=613;aulast=Mengnerve regeneration; brain injury; repetitive transcranial magnetic stimulation; motor dysfunction; cerebral infarction; National Institute of Health Stroke Scale; Barthel Index; Fugl-Meyer Assessment; neural regeneration
spellingShingle Zhi-yong Meng
Wei-qun Song
Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction
Neural Regeneration Research
nerve regeneration; brain injury; repetitive transcranial magnetic stimulation; motor dysfunction; cerebral infarction; National Institute of Health Stroke Scale; Barthel Index; Fugl-Meyer Assessment; neural regeneration
title Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction
title_full Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction
title_fullStr Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction
title_full_unstemmed Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction
title_short Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction
title_sort low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction
topic nerve regeneration; brain injury; repetitive transcranial magnetic stimulation; motor dysfunction; cerebral infarction; National Institute of Health Stroke Scale; Barthel Index; Fugl-Meyer Assessment; neural regeneration
url http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=4;spage=610;epage=613;aulast=Meng
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