Antifibrotic mechanism of avitinib in bleomycin-induced pulmonary fibrosis in mice

Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterized by alveolar epithelial cell injury and lung fibroblast overactivation. At present, only two drugs are approved by the FDA for the treatment of IPF, including the synthetic pyridinone drug,...

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Autori principali: Yang Miao, Yanhua Wang, Zhun Bi, Kai Huang, Jingjing Gao, Xiaohe Li, Shimeng Li, Luqing Wei, Honggang Zhou, Cheng Yang
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2023-03-01
Serie:BMC Pulmonary Medicine
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Accesso online:https://doi.org/10.1186/s12890-023-02385-9