IRAK4 and TLR3 sequence variants may alter breast cancer risk among African-American women

IRAK4 and TLR3 sequence variants may alter breast cancer risk among African-American women

Mounting evidence suggests that imbalances in immune regulation contribute to cell transformation. Women of African descent are an understudied group at high risk for developing aggressive breast cancer (BrCa). Therefore, we examined the role of 16 innate immune single nucleotide polymorphisms (SNP...

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Bibliographic Details
Main Authors: Susan Taylor Yeyeodu, La Cries Renee Kidd, Gabriela M. Oprea, Tiva Templeton Vancleave, Joong-Youn eShim, Kevin Sean Kimbro
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Immunology
Subjects:
TLR3
innate immunity
breast cancer
Single nucleotide polymorphism
African American
IRAK-4
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00338/full

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