Cells with dyskeratotic ínclusions in smears from cervix uteri infected by human papillomavírus

An additional feature has been reported in cervical smears from patients with human papillomavirus (HPV) infection: the “cell inside another cell”, that shows inclusion bodies in addition to a nuclear smudging (cell with dyskeratotic inclusions: CDl). We observed smears from 129 patients with diagn...

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Bibliographic Details
Main Authors: Luis Alberto Palaoro, Marcelo Szulc, Juan Carlos Giogrande
Format: Article
Language:English
Published: Instituto Nacional de Câncer (INCA) 2022-09-01
Series:Revista Brasileira de Cancerologia
Online Access:https://rbc.inca.gov.br/index.php/revista/article/view/2771
Description
Summary:An additional feature has been reported in cervical smears from patients with human papillomavirus (HPV) infection: the “cell inside another cell”, that shows inclusion bodies in addition to a nuclear smudging (cell with dyskeratotic inclusions: CDl). We observed smears from 129 patients with diagnosis of HPV infection ofthe cervix uteri, stained by Papanicolaou technique. Koilocytes were observed in 48,8% of the patients, and CDI in 30,2% of them. CDI wes presented by 19,3% of the patients. The CDl could not be related to a special type of HPV, therefore it is not a parameter for estimation ofthe oncogenic risk. Further studies are needed to clarify if CDl could be other indirect feature suggestive of HPV infection.
ISSN:2176-9745