Bacterial Nanocellulose Hydrogel: A Promising Alternative Material for the Fabrication of Engineered Vascular Grafts
Blood vessels are crucial in the human body, providing essential nutrients to all tissues while facilitating waste removal. As the incidence of cardiovascular disease rises, the demand for efficient treatments increases concurrently. Currently, the predominant interventions for cardiovascular diseas...
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Format: | Article |
Language: | English |
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MDPI AG
2023-09-01
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Series: | Polymers |
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Online Access: | https://www.mdpi.com/2073-4360/15/18/3812 |
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author | Daichen Liu Qingshan Meng Jinguang Hu |
author_facet | Daichen Liu Qingshan Meng Jinguang Hu |
author_sort | Daichen Liu |
collection | DOAJ |
description | Blood vessels are crucial in the human body, providing essential nutrients to all tissues while facilitating waste removal. As the incidence of cardiovascular disease rises, the demand for efficient treatments increases concurrently. Currently, the predominant interventions for cardiovascular disease are autografts and allografts. Although effective, they present limitations including high costs and inconsistent success rates. Recently, synthetic vascular grafts, made from artificial materials, have emerged as promising alternatives to traditional methods. Among these materials, bacterial cellulose hydrogel exhibits significant potential for tissue engineering applications, particularly in developing nanoscale platforms that regulate cell behavior and promote tissue regeneration, attributed to its notable physicochemical and biocompatible properties. This study reviews recent progress in fabricating engineered vascular grafts using bacterial nanocellulose, demonstrating the efficacy of bacterial cellulose hydrogel as a biomaterial for synthetic vascular grafts, specifically for stimulating angiogenesis and neovascularization. |
first_indexed | 2024-03-10T22:11:31Z |
format | Article |
id | doaj.art-87801160fbd04bfbbbdab4c35ebfc005 |
institution | Directory Open Access Journal |
issn | 2073-4360 |
language | English |
last_indexed | 2024-03-10T22:11:31Z |
publishDate | 2023-09-01 |
publisher | MDPI AG |
record_format | Article |
series | Polymers |
spelling | doaj.art-87801160fbd04bfbbbdab4c35ebfc0052023-11-19T12:36:10ZengMDPI AGPolymers2073-43602023-09-011518381210.3390/polym15183812Bacterial Nanocellulose Hydrogel: A Promising Alternative Material for the Fabrication of Engineered Vascular GraftsDaichen Liu0Qingshan Meng1Jinguang Hu2Department of Chemical and Petroleum Engineering, University of Calgary, 2500 University Drive, Calgary, AB T2N 1N4, CanadaDepartment of Chemical and Petroleum Engineering, University of Calgary, 2500 University Drive, Calgary, AB T2N 1N4, CanadaDepartment of Chemical and Petroleum Engineering, University of Calgary, 2500 University Drive, Calgary, AB T2N 1N4, CanadaBlood vessels are crucial in the human body, providing essential nutrients to all tissues while facilitating waste removal. As the incidence of cardiovascular disease rises, the demand for efficient treatments increases concurrently. Currently, the predominant interventions for cardiovascular disease are autografts and allografts. Although effective, they present limitations including high costs and inconsistent success rates. Recently, synthetic vascular grafts, made from artificial materials, have emerged as promising alternatives to traditional methods. Among these materials, bacterial cellulose hydrogel exhibits significant potential for tissue engineering applications, particularly in developing nanoscale platforms that regulate cell behavior and promote tissue regeneration, attributed to its notable physicochemical and biocompatible properties. This study reviews recent progress in fabricating engineered vascular grafts using bacterial nanocellulose, demonstrating the efficacy of bacterial cellulose hydrogel as a biomaterial for synthetic vascular grafts, specifically for stimulating angiogenesis and neovascularization.https://www.mdpi.com/2073-4360/15/18/3812bacterial nanocellulosevascular graftsnatural hydrogel |
spellingShingle | Daichen Liu Qingshan Meng Jinguang Hu Bacterial Nanocellulose Hydrogel: A Promising Alternative Material for the Fabrication of Engineered Vascular Grafts Polymers bacterial nanocellulose vascular grafts natural hydrogel |
title | Bacterial Nanocellulose Hydrogel: A Promising Alternative Material for the Fabrication of Engineered Vascular Grafts |
title_full | Bacterial Nanocellulose Hydrogel: A Promising Alternative Material for the Fabrication of Engineered Vascular Grafts |
title_fullStr | Bacterial Nanocellulose Hydrogel: A Promising Alternative Material for the Fabrication of Engineered Vascular Grafts |
title_full_unstemmed | Bacterial Nanocellulose Hydrogel: A Promising Alternative Material for the Fabrication of Engineered Vascular Grafts |
title_short | Bacterial Nanocellulose Hydrogel: A Promising Alternative Material for the Fabrication of Engineered Vascular Grafts |
title_sort | bacterial nanocellulose hydrogel a promising alternative material for the fabrication of engineered vascular grafts |
topic | bacterial nanocellulose vascular grafts natural hydrogel |
url | https://www.mdpi.com/2073-4360/15/18/3812 |
work_keys_str_mv | AT daichenliu bacterialnanocellulosehydrogelapromisingalternativematerialforthefabricationofengineeredvasculargrafts AT qingshanmeng bacterialnanocellulosehydrogelapromisingalternativematerialforthefabricationofengineeredvasculargrafts AT jinguanghu bacterialnanocellulosehydrogelapromisingalternativematerialforthefabricationofengineeredvasculargrafts |