Evaluation of Cumulative Effect of Standard Triple Immunosuppression on Prevention of De Novo Donor Specific Antibodies (dnDSA) Production in Children after Kidney Transplantation—A Retrospective and Prospective Study

Evaluation of Cumulative Effect of Standard Triple Immunosuppression on Prevention of De Novo Donor Specific Antibodies (dnDSA) Production in Children after Kidney Transplantation—A Retrospective and Prospective Study

De novo Donor Specific Antibodies (dnDSA) are associated with inferior graft outcomes. Standard immunosuppression is expected to prevent dnDSA production in low-risk patients. We have evaluated a cumulative effect of a triple immunosuppression (CNI/MMF/Pred), as well as TAC concentration and coeffic...

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Bibliographic Details
Main Authors: Agnieszka Urzykowska, Barbara Piątosa, Urszula Grycuk, Grzegorz Kowalewski, Zbigniew Kułaga, Ryszard Grenda
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Children
Subjects:
Vasudev score
cumulative strength of immunosuppression
TAC variability and concentration
dnDSA
kidney transplantation
Online Access:https://www.mdpi.com/2227-9067/8/12/1162

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