Comparison of Rubella, Cytomegalovirus, Toxoplasma gondii seroprevalence, Still Birth and Preterm Birth Rates in Pregnant Patients Admitted to Our Hospital, IgG Avidity in IgG Positive Patients
INTRODUCTION: The aim of this study is to identify seroprevalence of Rubella, Cytomegalovirus and T. gondii in pregnancies, determination of stillbirth and preterm delivery rates and comparison of IgG avidity with avidity in pregnant patients with positive IgG antibodies. METHODS: The study was carr...
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| Format: | Article |
| Language: | English |
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Van Yuzuncu Yil University, School of Medicine
2021-04-01
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| Series: | Van Tıp Dergisi |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-54036 |
| _version_ | 1797426411969970176 |
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| author | Esra Gürbüz Ali Irfan Baran |
| author_facet | Esra Gürbüz Ali Irfan Baran |
| author_sort | Esra Gürbüz |
| collection | DOAJ |
| description | INTRODUCTION: The aim of this study is to identify seroprevalence of Rubella, Cytomegalovirus and T. gondii in pregnancies, determination of stillbirth and preterm delivery rates and comparison of IgG avidity with avidity in pregnant patients with positive IgG antibodies. METHODS: The study was carried out by ELISA method in order to investigate Cytomegalovirus, Rubella and T.gondii IgG and IgM antibodies in 300 blood samples taken from pregnant patients between the ages of 18-48 who applied to the Gynecology and Obstetrics Outpatient Clinic.
RESULTS: Rubella IgG 96% and Rubella IgM 4%, CMV IgG 99%, CMV IgM 1.3%, T. gondii IgG 56.3% and IgM 7.6% seropositivity were detected in pregnant blood samples. The ratios of stillbirth and preterm delivery are respectively determined as Rubella IgM 2 (18.1%) / 4 (17.3%), Rubella IgG 11 (100%) / 22 (95.6%) and CMV IgM 1 (9%) / 2 (8,3%), CMV IgG 11 (100%) / 23 (100%), T. gondii IgM 1 (9%) / 3 (13%), T. gondii IgG 4 (34.7%). The avidity values were determined as 3/0/2 in Rubella, 0/0/3 in Cytomegalovirus and 8/1/12 in T. gondii in low / gray zone / high values respectively DISCUSSION AND CONCLUSION: As a result, Toxoplasma gondii, Cytomegalovirus and Rubella, which may cause aborts or stillbirths, are among the important health problems in pregnant patients in our region. It has been concluded that serologic methods may be a method of guiding medicine in diagnosing these infections and clarifying suspicious cases by performing IgG avidity test. |
| first_indexed | 2024-03-09T08:29:51Z |
| format | Article |
| id | doaj.art-87846941eb704022a0ac0e3e16cc3938 |
| institution | Directory Open Access Journal |
| issn | 2587-0351 |
| language | English |
| last_indexed | 2024-03-09T08:29:51Z |
| publishDate | 2021-04-01 |
| publisher | Van Yuzuncu Yil University, School of Medicine |
| record_format | Article |
| series | Van Tıp Dergisi |
| spelling | doaj.art-87846941eb704022a0ac0e3e16cc39382023-12-02T20:22:30ZengVan Yuzuncu Yil University, School of MedicineVan Tıp Dergisi2587-03512021-04-0128230030610.5505/vtd.2021.54036VTD-54036Comparison of Rubella, Cytomegalovirus, Toxoplasma gondii seroprevalence, Still Birth and Preterm Birth Rates in Pregnant Patients Admitted to Our Hospital, IgG Avidity in IgG Positive PatientsEsra Gürbüz0Ali Irfan Baran1Van Training And Research Hospital, Infectious Diseases And Clinical Microbiology, VanYüzüncü Yıl University Dursun Odabaş Medical Center, Infectious Diseases And Clinical Microbiology, VanINTRODUCTION: The aim of this study is to identify seroprevalence of Rubella, Cytomegalovirus and T. gondii in pregnancies, determination of stillbirth and preterm delivery rates and comparison of IgG avidity with avidity in pregnant patients with positive IgG antibodies. METHODS: The study was carried out by ELISA method in order to investigate Cytomegalovirus, Rubella and T.gondii IgG and IgM antibodies in 300 blood samples taken from pregnant patients between the ages of 18-48 who applied to the Gynecology and Obstetrics Outpatient Clinic. RESULTS: Rubella IgG 96% and Rubella IgM 4%, CMV IgG 99%, CMV IgM 1.3%, T. gondii IgG 56.3% and IgM 7.6% seropositivity were detected in pregnant blood samples. The ratios of stillbirth and preterm delivery are respectively determined as Rubella IgM 2 (18.1%) / 4 (17.3%), Rubella IgG 11 (100%) / 22 (95.6%) and CMV IgM 1 (9%) / 2 (8,3%), CMV IgG 11 (100%) / 23 (100%), T. gondii IgM 1 (9%) / 3 (13%), T. gondii IgG 4 (34.7%). The avidity values were determined as 3/0/2 in Rubella, 0/0/3 in Cytomegalovirus and 8/1/12 in T. gondii in low / gray zone / high values respectively DISCUSSION AND CONCLUSION: As a result, Toxoplasma gondii, Cytomegalovirus and Rubella, which may cause aborts or stillbirths, are among the important health problems in pregnant patients in our region. It has been concluded that serologic methods may be a method of guiding medicine in diagnosing these infections and clarifying suspicious cases by performing IgG avidity test.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-54036pregnancyseroprevalencetoxoplasma gondiicmvrubellaavidite |
| spellingShingle | Esra Gürbüz Ali Irfan Baran Comparison of Rubella, Cytomegalovirus, Toxoplasma gondii seroprevalence, Still Birth and Preterm Birth Rates in Pregnant Patients Admitted to Our Hospital, IgG Avidity in IgG Positive Patients Van Tıp Dergisi pregnancy seroprevalence toxoplasma gondii cmv rubella avidite |
| title | Comparison of Rubella, Cytomegalovirus, Toxoplasma gondii seroprevalence, Still Birth and Preterm Birth Rates in Pregnant Patients Admitted to Our Hospital, IgG Avidity in IgG Positive Patients |
| title_full | Comparison of Rubella, Cytomegalovirus, Toxoplasma gondii seroprevalence, Still Birth and Preterm Birth Rates in Pregnant Patients Admitted to Our Hospital, IgG Avidity in IgG Positive Patients |
| title_fullStr | Comparison of Rubella, Cytomegalovirus, Toxoplasma gondii seroprevalence, Still Birth and Preterm Birth Rates in Pregnant Patients Admitted to Our Hospital, IgG Avidity in IgG Positive Patients |
| title_full_unstemmed | Comparison of Rubella, Cytomegalovirus, Toxoplasma gondii seroprevalence, Still Birth and Preterm Birth Rates in Pregnant Patients Admitted to Our Hospital, IgG Avidity in IgG Positive Patients |
| title_short | Comparison of Rubella, Cytomegalovirus, Toxoplasma gondii seroprevalence, Still Birth and Preterm Birth Rates in Pregnant Patients Admitted to Our Hospital, IgG Avidity in IgG Positive Patients |
| title_sort | comparison of rubella cytomegalovirus toxoplasma gondii seroprevalence still birth and preterm birth rates in pregnant patients admitted to our hospital igg avidity in igg positive patients |
| topic | pregnancy seroprevalence toxoplasma gondii cmv rubella avidite |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-54036 |
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