Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier

Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier

Inflammatory bowel disease (IBD) comprises systemic inflammatory conditions primarily affecting the gastrointestinal tract, including Crohn’s disease and ulcerative colitis. This research aims to analyze the clinical symptoms and pathogenesis of a Dextran sodium sulfate (DSS)-induced canine IBD mode...

Full description

Bibliographic Details
Main Authors:	Aipeng Mao, Weigang Zhao, Yuhang Zhu, Fantao Kong, Danyang Chen, Huazhe Si, Chao Xu
Format:	Article
Language:	English
Published:	MDPI AG 2023-10-01
Series:	Microorganisms
Subjects:	ginsenoside inflammatory bowel disease tight junction protein adherens junction protein mucosal bacterial community
Online Access:	https://www.mdpi.com/2076-2607/11/11/2616

Similar Items

Molecular Characterization of the Extracellular Domain of Human Junctional Adhesion Proteins
by: Christopher Mendoza, et al.
Published: (2021-03-01)

Adherens, tight, and gap junctions in ependymal cells: A systematic review of their contribution to CSF-brain barrier
by: Riccardo Serra, et al.
Published: (2023-03-01)

RETRACTED ARTICLE: Protective role of p120-catenin in maintaining the integrity of adherens and tight junctions in ventilator-induced lung injury
by: Changping Gu, et al.
Published: (2015-05-01)

Imbalance of Pulmonary Microvascular Endothelial Cell-Expression of Metalloproteinases and Their Endogenous Inhibitors Promotes Septic Barrier Dysfunction
by: Devika P. Jayawardena, et al.
Published: (2023-04-01)

Loss of Endothelial Barrier Function in the Inflammatory Setting: Indication for a Cytokine-Mediated Post-Transcriptional Mechanism by Virtue of Upregulation of miRNAs miR-29a-3p, miR-29b-3p, and miR-155-5p
by: Daniel Maucher, et al.
Published: (2021-10-01)

The Regulation of Intestinal Mucosal Barrier by Myosin Light Chain Kinase/Rho Kinases
by: Younggeon Jin, et al.
Published: (2020-05-01)

Diversity of Intercellular Communication Modes: A Cancer Biology Perspective
by: Thanzeela Ebrahim, et al.
Published: (2024-03-01)

Airway Epithelial Cell Junctions as Targets for Pathogens and Antimicrobial Therapy
by: Nannan Gao, et al.
Published: (2022-11-01)

Regulation of Epithelial and Endothelial Barriers by Molecular Chaperones
by: Susana Lechuga, et al.
Published: (2024-02-01)

Effect of Graphene and Graphene Oxide on Airway Barrier and Differential Phosphorylation of Proteins in Tight and Adherens Junction Pathways
by: Sofie Van Den Broucke, et al.
Published: (2021-05-01)

Role of Cell-Cell Junctions in Oesophageal Squamous Cell Carcinoma
by: Qian-Rui Xu, et al.
Published: (2022-09-01)

Role of Intermediate Filaments in Blood–Brain Barrier in Health and Disease
by: Ece Bayir, et al.
Published: (2021-06-01)

Costunolide and parthenolide: Novel blood-brain barrier permeable sesquiterpene lactones to improve barrier tightness
by: María Ángeles Ávila-Gálvez, et al.
Published: (2023-11-01)

Overview of junctional complexes during mammalian early embryonic development
by: Ceren Canse, et al.
Published: (2023-04-01)

Effects of acute and chronic disease on cell junctions in mouse liver
by: Raf Van Campenhout, et al.
Published: (2023-01-01)

Exposure to Zinc Oxide Nanoparticles Disrupts Endothelial Tight and Adherens Junctions and Induces Pulmonary Inflammatory Cell Infiltration
by: Chen-Mei Chen, et al.
Published: (2020-05-01)

Improvement of the intestinal epithelial barrier during laxative effects of phlorotannin in loperamide-induced constipation of SD rats
by: Ji Eun Kim, et al.
Published: (2023-01-01)

Ginsenoside Re protects rhinovirus-induced disruption of tight junction through inhibition of ROS-mediated phosphatases inactivation in human nasal epithelial cells
by: Kyeong Ah Kim, et al.
Published: (2024-03-01)

What do we know about blood-testis barrier? current understanding of its structure and physiology
by: J. P. Luaces, et al.
Published: (2023-06-01)

Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy
by: Hui Zou, et al.
Published: (2020-10-01)

Ginsenosides repair UVB-induced skin barrier damage in BALB/c hairless mice and HaCaT keratinocytes
by: Zhenzhuo Li, et al.
Published: (2022-01-01)

The Cx43 Carboxyl-Terminal Mimetic Peptide αCT1 Protects Endothelial Barrier Function in a ZO1 Binding-Competent Manner
by: Randy E. Strauss, et al.
Published: (2021-08-01)

Palmitic Acid Affects Intestinal Epithelial Barrier Integrity and Permeability In Vitro
by: Manuele Gori, et al.
Published: (2020-05-01)

Flavivirus NS1 Triggers Tissue-Specific Disassembly of Intercellular Junctions Leading to Barrier Dysfunction and Vascular Leak in a GSK-3β-Dependent Manner
by: Henry Puerta-Guardo, et al.
Published: (2022-05-01)

Correction: Mao et al. Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier. <i>Microorganisms</i> 2023, <i>11</i>, 2616
by: Aipeng Mao, et al.
Published: (2024-01-01)

The Effect of Probiotics on Intestinal Tight Junction Protein Expression in Animal Models: A Meta-Analysis
by: Sung-Il Ahn, et al.
Published: (2022-05-01)

Dynamic Changes in Colonic Structure and Protein Expression Suggest Regulatory Mechanisms of Colonic Barrier Function in Torpor–Arousal Cycles of the Daurian Ground Squirrel
by: Weilan Miao, et al.
Published: (2022-08-01)

Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis
by: Claire Bardet, et al.
Published: (2017-05-01)

Vitamin D Promotes Mucosal Barrier System of Fish Skin Infected with <i>Aeromonas hydrophila</i> through Multiple Modulation of Physical and Immune Protective Capacity
by: Yao Zhang, et al.
Published: (2023-07-01)

Nectin4 is a potential therapeutic target for asthma
by: Pureun-Haneul Lee, et al.
Published: (2022-11-01)

CmPn/CmP Signaling Networks in the Maintenance of the Blood Vessel Barrier
by: Revathi Gnanasekaran, et al.
Published: (2023-04-01)

ESCRT-III-dependent adhesive and mechanical changes are triggered by a mechanism detecting alteration of septate junction integrity in Drosophila epithelial cells
by: Thomas Esmangart de Bournonville, et al.
Published: (2024-02-01)

Barriers and channels formed by tight junction proteins II /
by: Fromm, Michael, et al.
Published: (2012)

Alteration of Colonic Mucosal Permeability during Antibiotic-Induced Dysbiosis
by: Ying Ran, et al.
Published: (2020-08-01)

Effect of Heat-Killed <i>Lactobacillus casei</i> DKGF7 on a Rat Model of Irritable Bowel Syndrome
by: Gyeol Seong, et al.
Published: (2021-02-01)

SDH, a novel diarylheptane compound, is a potential treatment for inflammatory bowel disease by restoring epithelial barrier function
by: Fei Yang, et al.
Published: (2022-07-01)

Is IIIG9 a New Protein with Exclusive Ciliary Function? Analysis of Its Potential Role in Cancer and Other Pathologies
by: María José Oviedo, et al.
Published: (2022-10-01)

JAK-STAT Pathway Regulation of Intestinal Permeability: Pathogenic Roles and Therapeutic Opportunities in Inflammatory Bowel Disease
by: Hillmin Lei, et al.
Published: (2021-08-01)

Liposomal encapsulated oregano, cinnamon, and clove oils enhanced the performance, bacterial metabolites antioxidant potential, and intestinal microbiota of broiler chickens
by: Ahmed M.A. Meligy, et al.
Published: (2023-06-01)

Adipsin alleviates cardiac microvascular injury in diabetic cardiomyopathy through Csk-dependent signaling mechanism
by: Xuebin Zhang, et al.
Published: (2023-05-01)