miR-200 enhances mouse breast cancer cell colonization to form distant metastases.
BACKGROUND:The development of metastases involves the dissociation of cells from the primary tumor to penetrate the basement membrane, invade and then exit the vasculature to seed, and colonize distant tissues. The last step, establishment of macroscopic tumors at distant sites, is the least well un...
Main Authors: | Derek M Dykxhoorn, Yichao Wu, Huangming Xie, Fengyan Yu, Ashish Lal, Fabio Petrocca, Denis Martinvalet, Erwei Song, Bing Lim, Judy Lieberman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-09-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2749331?pdf=render |
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