Evaluation and Catheter Ablation of Ventricular Arrhythmias in Cardiac Sarcoidosis

Ventricular arrhythmias are a common clinical manifestation in patients with cardiac sarcoidosis (CS) and other arrhythmogenic inflammatory cardiomyopathies (AIC). The management of sustained ventricular arrhythmias in these patients presents unique challenges. Current therapies include immunosuppre...

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Main Authors: Fatima M. Ezzeddine, Nicholas Tan, Konstantinos C. Siontis
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/22/6718
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author Fatima M. Ezzeddine
Nicholas Tan
Konstantinos C. Siontis
author_facet Fatima M. Ezzeddine
Nicholas Tan
Konstantinos C. Siontis
author_sort Fatima M. Ezzeddine
collection DOAJ
description Ventricular arrhythmias are a common clinical manifestation in patients with cardiac sarcoidosis (CS) and other arrhythmogenic inflammatory cardiomyopathies (AIC). The management of sustained ventricular arrhythmias in these patients presents unique challenges. Current therapies include immunosuppressive, antiarrhythmic agents, and catheter ablation. Significant progress has been made in deciphering the importance of patient selection for ablation, systematic preablation evaluation, and optimal ablation timing, as well as ablation approaches and techniques. In this overview, we discuss the evaluation and management of ventricular arrhythmias in patients with CS, focusing on catheter ablation, which has evolved into an effective approach in reducing the burden of ventricular arrhythmias in these patients in the context of multifaceted treatment along with medical therapies.
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spelling doaj.art-878a12c2ffcb4ddea399e9b4466401d12023-11-24T08:48:58ZengMDPI AGJournal of Clinical Medicine2077-03832022-11-011122671810.3390/jcm11226718Evaluation and Catheter Ablation of Ventricular Arrhythmias in Cardiac SarcoidosisFatima M. Ezzeddine0Nicholas Tan1Konstantinos C. Siontis2Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USADepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USADepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USAVentricular arrhythmias are a common clinical manifestation in patients with cardiac sarcoidosis (CS) and other arrhythmogenic inflammatory cardiomyopathies (AIC). The management of sustained ventricular arrhythmias in these patients presents unique challenges. Current therapies include immunosuppressive, antiarrhythmic agents, and catheter ablation. Significant progress has been made in deciphering the importance of patient selection for ablation, systematic preablation evaluation, and optimal ablation timing, as well as ablation approaches and techniques. In this overview, we discuss the evaluation and management of ventricular arrhythmias in patients with CS, focusing on catheter ablation, which has evolved into an effective approach in reducing the burden of ventricular arrhythmias in these patients in the context of multifaceted treatment along with medical therapies.https://www.mdpi.com/2077-0383/11/22/6718cardiac sarcoidosiscatheter ablationventricular arrhythmias
spellingShingle Fatima M. Ezzeddine
Nicholas Tan
Konstantinos C. Siontis
Evaluation and Catheter Ablation of Ventricular Arrhythmias in Cardiac Sarcoidosis
Journal of Clinical Medicine
cardiac sarcoidosis
catheter ablation
ventricular arrhythmias
title Evaluation and Catheter Ablation of Ventricular Arrhythmias in Cardiac Sarcoidosis
title_full Evaluation and Catheter Ablation of Ventricular Arrhythmias in Cardiac Sarcoidosis
title_fullStr Evaluation and Catheter Ablation of Ventricular Arrhythmias in Cardiac Sarcoidosis
title_full_unstemmed Evaluation and Catheter Ablation of Ventricular Arrhythmias in Cardiac Sarcoidosis
title_short Evaluation and Catheter Ablation of Ventricular Arrhythmias in Cardiac Sarcoidosis
title_sort evaluation and catheter ablation of ventricular arrhythmias in cardiac sarcoidosis
topic cardiac sarcoidosis
catheter ablation
ventricular arrhythmias
url https://www.mdpi.com/2077-0383/11/22/6718
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