The Protective Efficacy of Single-Dose Nasal Immunization with Cold-Adapted Live-Attenuated MERS-CoV Vaccine against Lethal MERS-CoV Infections in Mice

The Protective Efficacy of Single-Dose Nasal Immunization with Cold-Adapted Live-Attenuated MERS-CoV Vaccine against Lethal MERS-CoV Infections in Mice

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe diseases in humans. Camels act as intermediate hosts for MERS-CoV. Currently, no licensed vaccine is available for this virus. We have developed a potential candidate vaccine for MERS-CoV using the cold adaptation method. We culti...

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Bibliographic Details
Main Authors: Heejeong Seo, Yunyueng Jang, Dongmi Kwak
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Vaccines
Subjects:
MERS-CoV
live-attenuated
vaccine
cold-adapted
Online Access:https://www.mdpi.com/2076-393X/11/8/1353

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