NHC-catalyzed regiodivergent transformations of Ynones with trifluoromethyl ketones: Aldol reaction or [3+2] annulation

NHC-catalyzed regiodivergent transformations of Ynones with trifluoromethyl ketones: Aldol reaction or [3+2] annulation

A novel NHC-catalyzed regiodivergent reaction of ynones with trifluoromethyl ketones consisting of Aldol reactions and intermolecular [3 + 2] annulations has been developed. Employing two different NHC catalysts, various tertiary alcohols and dihyrofuranones containing trifluoromethyl can be obtaine...

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Bibliographic Details
Main Authors: Fangfang Lu, Bai Shi, Wei Cao, Huiping Yin, Tianjiao Huang, Kai Zhang, Changsheng Yao
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Tetrahedron Chem
Subjects:
NHC catalysis
Regiodivergence
ynones
Aldol reaction
[3+2] annulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666951X23000104

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