A Study of the Relationship Between Uric Acid and Substantia Nigra Brain Connectivity in Patients With REM Sleep Behavior Disorder and Parkinson's Disease

A Study of the Relationship Between Uric Acid and Substantia Nigra Brain Connectivity in Patients With REM Sleep Behavior Disorder and Parkinson's Disease

Low levels of the natural antioxidant uric acid (UA) and the presence of REM sleep behavior disorder (RBD) are both associated with an increased likelihood of developing Parkinson's disease (PD). RBD and PD are also accompanied by basal ganglia dysfunction including decreased nigrostriatal and...

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Bibliographic Details
Main Authors: Timothy M. Ellmore, Jessika Suescun, Richard J. Castriotta, Mya C. Schiess
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neurology
Subjects:
uric acid
REM sleep behavior disorder
parkinson's disease
resting state
functional connectivity
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00815/full

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