Biological therapies in Crohn’s disease
Crohn’s disease is one of the chronic inflammatory diseases of the digestive tract. Pathophysiology of this disease involves the genetic and environmental factors, but the most important causative factor is anti-inflammatory reaction of the organism, which eventually leads to inflammatory changes, f...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2018-09-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/26383 |
| _version_ | 1818249176520065024 |
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| author | Patryk Kaczor Katarzyna Lipa Magdalena Julia Jabłońska Kamil Leis Krystian Kałużny Przemysław Gałązka |
| author_facet | Patryk Kaczor Katarzyna Lipa Magdalena Julia Jabłońska Kamil Leis Krystian Kałużny Przemysław Gałązka |
| author_sort | Patryk Kaczor |
| collection | DOAJ |
| description | Crohn’s disease is one of the chronic inflammatory diseases of the digestive tract. Pathophysiology of this disease involves the genetic and environmental factors, but the most important causative factor is anti-inflammatory reaction of the organism, which eventually leads to inflammatory changes, fibrosis and necrosis. Glucocorticosteroids are commonly used in therapy and may cause many negative side effects. Nowadays, new biological medicines are being tested, which are supposed to be an alternative method of treating Crohn’s disease. Infliximab, adalimumab, certolizumab pegol, natalizumab, etanerecept, vedolizumab and ustekinumab are the examples of those drugs, on which the research was already carried out. They lead to healing of the mucous membrane of the digestive tract, and thus to remission of the disease. |
| first_indexed | 2024-12-12T15:32:20Z |
| format | Article |
| id | doaj.art-879100090969416daf4ea3bff305168a |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-12T15:32:20Z |
| publishDate | 2018-09-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-879100090969416daf4ea3bff305168a2022-12-22T00:20:05ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062018-09-0189Biological therapies in Crohn’s diseasePatryk Kaczor0Katarzyna Lipa1Magdalena Julia Jabłońska2Kamil Leis3Krystian Kałużny4Przemysław Gałązka5Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in ToruńLudwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in ToruńLudwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in ToruńLudwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in ToruńLudwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in ToruńAntoni Jurasz University Hospital No. 1 in Bydgoszcz, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in ToruńCrohn’s disease is one of the chronic inflammatory diseases of the digestive tract. Pathophysiology of this disease involves the genetic and environmental factors, but the most important causative factor is anti-inflammatory reaction of the organism, which eventually leads to inflammatory changes, fibrosis and necrosis. Glucocorticosteroids are commonly used in therapy and may cause many negative side effects. Nowadays, new biological medicines are being tested, which are supposed to be an alternative method of treating Crohn’s disease. Infliximab, adalimumab, certolizumab pegol, natalizumab, etanerecept, vedolizumab and ustekinumab are the examples of those drugs, on which the research was already carried out. They lead to healing of the mucous membrane of the digestive tract, and thus to remission of the disease.https://apcz.umk.pl/JEHS/article/view/26383Crohn’s diseasechronic inflammatory diseasebiological therapy |
| spellingShingle | Patryk Kaczor Katarzyna Lipa Magdalena Julia Jabłońska Kamil Leis Krystian Kałużny Przemysław Gałązka Biological therapies in Crohn’s disease Journal of Education, Health and Sport Crohn’s disease chronic inflammatory disease biological therapy |
| title | Biological therapies in Crohn’s disease |
| title_full | Biological therapies in Crohn’s disease |
| title_fullStr | Biological therapies in Crohn’s disease |
| title_full_unstemmed | Biological therapies in Crohn’s disease |
| title_short | Biological therapies in Crohn’s disease |
| title_sort | biological therapies in crohn s disease |
| topic | Crohn’s disease chronic inflammatory disease biological therapy |
| url | https://apcz.umk.pl/JEHS/article/view/26383 |
| work_keys_str_mv | AT patrykkaczor biologicaltherapiesincrohnsdisease AT katarzynalipa biologicaltherapiesincrohnsdisease AT magdalenajuliajabłonska biologicaltherapiesincrohnsdisease AT kamilleis biologicaltherapiesincrohnsdisease AT krystiankałuzny biologicaltherapiesincrohnsdisease AT przemysławgałazka biologicaltherapiesincrohnsdisease |