The first steps in vision: cell types, circuits, and repair
Abstract Dysfunction of the key sense of vision, leading to visual handicap or blindness, has a crucial effect on day‐to‐day life. In this commentary, I will summarize the work in my laboratory that is focused on a basic understanding of visual processing and the use of this information to understan...
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| Format: | Article |
| Language: | English |
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Springer Nature
2019-03-01
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| Series: | EMBO Molecular Medicine |
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| Online Access: | https://doi.org/10.15252/emmm.201810218 |
| _version_ | 1797284026467221504 |
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| author | Botond Roska |
| author_facet | Botond Roska |
| author_sort | Botond Roska |
| collection | DOAJ |
| description | Abstract Dysfunction of the key sense of vision, leading to visual handicap or blindness, has a crucial effect on day‐to‐day life. In this commentary, I will summarize the work in my laboratory that is focused on a basic understanding of visual processing and the use of this information to understand disease mechanism and to develop correcting therapies. We are beginning to understand how cell types of the visual system interact in local circuits and compute visual information. This has brought insight into mechanisms of cell‐type‐specific diseases and has allowed us to design new therapies for restoring vision in genetic forms of blindness. |
| first_indexed | 2024-03-07T17:43:01Z |
| format | Article |
| id | doaj.art-8791ae928d2f423ba86f85fd593dddb1 |
| institution | Directory Open Access Journal |
| issn | 1757-4676 1757-4684 |
| language | English |
| last_indexed | 2024-03-07T17:43:01Z |
| publishDate | 2019-03-01 |
| publisher | Springer Nature |
| record_format | Article |
| series | EMBO Molecular Medicine |
| spelling | doaj.art-8791ae928d2f423ba86f85fd593dddb12024-03-02T15:56:46ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842019-03-01113n/an/a10.15252/emmm.201810218The first steps in vision: cell types, circuits, and repairBotond Roska0Institute of Molecular and Clinical Ophthalmology Basel Basel SwitzerlandAbstract Dysfunction of the key sense of vision, leading to visual handicap or blindness, has a crucial effect on day‐to‐day life. In this commentary, I will summarize the work in my laboratory that is focused on a basic understanding of visual processing and the use of this information to understand disease mechanism and to develop correcting therapies. We are beginning to understand how cell types of the visual system interact in local circuits and compute visual information. This has brought insight into mechanisms of cell‐type‐specific diseases and has allowed us to design new therapies for restoring vision in genetic forms of blindness.https://doi.org/10.15252/emmm.201810218cell type‐specific gene therapyFRMD7neuronal circuitsretinal disordersvision |
| spellingShingle | Botond Roska The first steps in vision: cell types, circuits, and repair EMBO Molecular Medicine cell type‐specific gene therapy FRMD7 neuronal circuits retinal disorders vision |
| title | The first steps in vision: cell types, circuits, and repair |
| title_full | The first steps in vision: cell types, circuits, and repair |
| title_fullStr | The first steps in vision: cell types, circuits, and repair |
| title_full_unstemmed | The first steps in vision: cell types, circuits, and repair |
| title_short | The first steps in vision: cell types, circuits, and repair |
| title_sort | first steps in vision cell types circuits and repair |
| topic | cell type‐specific gene therapy FRMD7 neuronal circuits retinal disorders vision |
| url | https://doi.org/10.15252/emmm.201810218 |
| work_keys_str_mv | AT botondroska thefirststepsinvisioncelltypescircuitsandrepair AT botondroska firststepsinvisioncelltypescircuitsandrepair |