Depletion of Endothelial-Derived 2-AG Reduces Blood-Endothelial Barrier Integrity via Alteration of VE-Cadherin and the Phospho-Proteome

Depletion of Endothelial-Derived 2-AG Reduces Blood-Endothelial Barrier Integrity via Alteration of VE-Cadherin and the Phospho-Proteome

Mounting evidence supports the role of the endocannabinoid system in neurophysiology, including blood–brain barrier (BBB) function. Recent work has demonstrated that activation of endocannabinoid receptors can mitigate insults to the BBB during neurological disorders like traumatic brain injury, cor...

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Bibliographic Details
Main Authors:	Aidan A. Levine, Erika Liktor-Busa, Shreya Balasubramanian, Seph M. Palomino, Anya M. Burtman, Sarah A. Couture, Austin A. Lipinski, Paul R. Langlais, Tally M. Largent-Milnes
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Series:	International Journal of Molecular Sciences
Subjects:	endocannabinoid blood–brain barrier 2-AG DAGLα VE-cadherin
Online Access:	https://www.mdpi.com/1422-0067/25/1/531

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