Pathomorphological changes of rat’s tail intervertebral disks and vertebrae bodies at asymmetric static compression-distension in the experiment
Constant asymmetric static compression-distention (ASCD) of tail segments of the spine was performed in rats by tail stump sewing to its base in the experiment. In period of 1–3 months using histological method it was fixed that ASCD led to pathological changes in intervertebral disks and...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Romodanov Neurosurgery Institute
2011-09-01
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| Series: | Ukrainian Neurosurgical Journal |
| Online Access: | https://theunj.org/article/view/57798 |
| _version_ | 1797341867475468288 |
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| author | Valeriy Grigorovsky Mykhaylo Khyzhnyak Irina Vasileva Irina Shuba Yuriy Gafiychuk |
| author_facet | Valeriy Grigorovsky Mykhaylo Khyzhnyak Irina Vasileva Irina Shuba Yuriy Gafiychuk |
| author_sort | Valeriy Grigorovsky |
| collection | DOAJ |
| description |
Constant asymmetric static compression-distention (ASCD) of tail segments of the spine was performed in rats by tail stump sewing to its base in the experiment. In period of 1–3 months using histological method it was fixed that ASCD led to pathological changes in intervertebral disks and vertebrae bodies, mainly caused by ischemia and dystrophy. The most constant histologicaly expressed component of intervertebral disks’ damage — is macrofocal cell necrosis in collagen plate of the fibrous ring on the side of compression, accompanied by crumple, significant fiber prevalence and cracking of the plates with perifocal zone of chondrocyte proliferation, but these changed didn’t result in substitution of focal damage in terms of observation. Zones of notochondral cells necrosis were inconstantly noted in the structures of nucleus pulposus and closing plates of vertebrae bodies and small osteomedullary zones of necrosis — in epiphysis and epiphyseal cartilages of the vertebrae bodies. Changes of osseous epiphyses and epiphyseal cartilages height, adjoining to disk in ASCD zones of fibrous ring and also vertebrae bodies marginal ossificates were inconstant and had no correct character. |
| first_indexed | 2024-03-08T10:24:47Z |
| format | Article |
| id | doaj.art-8794312c840448a9a702c2c2085739a3 |
| institution | Directory Open Access Journal |
| issn | 2663-9084 2663-9092 |
| language | English |
| last_indexed | 2024-03-08T10:24:47Z |
| publishDate | 2011-09-01 |
| publisher | Romodanov Neurosurgery Institute |
| record_format | Article |
| series | Ukrainian Neurosurgical Journal |
| spelling | doaj.art-8794312c840448a9a702c2c2085739a32024-01-27T08:08:47ZengRomodanov Neurosurgery InstituteUkrainian Neurosurgical Journal2663-90842663-90922011-09-013596510.25305/unj.57798Pathomorphological changes of rat’s tail intervertebral disks and vertebrae bodies at asymmetric static compression-distension in the experimentValeriy Grigorovsky0Mykhaylo Khyzhnyak1Irina Vasileva2Irina Shuba3Yuriy Gafiychuk4Institute of Traumatology and Orthopedics, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, UkraineMilitary Medical Clinical Center of South Region, Odessa, Ukraine Constant asymmetric static compression-distention (ASCD) of tail segments of the spine was performed in rats by tail stump sewing to its base in the experiment. In period of 1–3 months using histological method it was fixed that ASCD led to pathological changes in intervertebral disks and vertebrae bodies, mainly caused by ischemia and dystrophy. The most constant histologicaly expressed component of intervertebral disks’ damage — is macrofocal cell necrosis in collagen plate of the fibrous ring on the side of compression, accompanied by crumple, significant fiber prevalence and cracking of the plates with perifocal zone of chondrocyte proliferation, but these changed didn’t result in substitution of focal damage in terms of observation. Zones of notochondral cells necrosis were inconstantly noted in the structures of nucleus pulposus and closing plates of vertebrae bodies and small osteomedullary zones of necrosis — in epiphysis and epiphyseal cartilages of the vertebrae bodies. Changes of osseous epiphyses and epiphyseal cartilages height, adjoining to disk in ASCD zones of fibrous ring and also vertebrae bodies marginal ossificates were inconstant and had no correct character.https://theunj.org/article/view/57798 |
| spellingShingle | Valeriy Grigorovsky Mykhaylo Khyzhnyak Irina Vasileva Irina Shuba Yuriy Gafiychuk Pathomorphological changes of rat’s tail intervertebral disks and vertebrae bodies at asymmetric static compression-distension in the experiment Ukrainian Neurosurgical Journal |
| title | Pathomorphological changes of rat’s tail intervertebral disks and vertebrae bodies at asymmetric static compression-distension in the experiment |
| title_full | Pathomorphological changes of rat’s tail intervertebral disks and vertebrae bodies at asymmetric static compression-distension in the experiment |
| title_fullStr | Pathomorphological changes of rat’s tail intervertebral disks and vertebrae bodies at asymmetric static compression-distension in the experiment |
| title_full_unstemmed | Pathomorphological changes of rat’s tail intervertebral disks and vertebrae bodies at asymmetric static compression-distension in the experiment |
| title_short | Pathomorphological changes of rat’s tail intervertebral disks and vertebrae bodies at asymmetric static compression-distension in the experiment |
| title_sort | pathomorphological changes of rat s tail intervertebral disks and vertebrae bodies at asymmetric static compression distension in the experiment |
| url | https://theunj.org/article/view/57798 |
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