Notch pathway modulation on bone marrow-derived vascular precursor cells regulates their angiogenic and wound healing potential.

Notch pathway modulation on bone marrow-derived vascular precursor cells regulates their angiogenic and wound healing potential.

Bone marrow (BM) derived vascular precursor cells (BM-PC, endothelial progenitors) are involved in normal and malignant angiogenesis, in ischemia and in wound healing. However, the mechanisms by which BM-PC stimulate the pre-existing endothelial cells at sites of vascular remodelling/recovery, and t...

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Bibliographic Details
Main Authors: Francisco Caiado, Carla Real, Tânia Carvalho, Sérgio Dias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2582964?pdf=render

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