Ristocetin dependent cofactor activity in von Willebrand disease diagnosis: Limitations of relying on a single measure

Ristocetin dependent cofactor activity in von Willebrand disease diagnosis: Limitations of relying on a single measure

Abstract Background Von Willebrand disease (VWD) is a common inherited bleeding disorder, however the diagnosis can be complicated by a subjective bleeding history and issues with some current von Willebrand factor (VWF) laboratory assays. Objectives In the Zimmerman Program, we sought to determine...

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Bibliographic Details
Main Authors: Pamela A. Christopherson, Sandra L. Haberichter, Veronica H. Flood, Ursula O. Sicking, Thomas C. Abshire, Robert R. Montgomery, the Zimmerman Program Investigators
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
clinical laboratory tests
genetic polymorphism
Ristocetin cofactor
von Willebrand disease
von Willebrand factor
Online Access:https://doi.org/10.1002/rth2.12807

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