Palmitic acid-activated GPRs/KLF7/CCL2 pathway is involved in the crosstalk between bone marrow adipocytes and prostate cancer

Palmitic acid-activated GPRs/KLF7/CCL2 pathway is involved in the crosstalk between bone marrow adipocytes and prostate cancer

Abstract Background Obesity-induced abnormal bone marrow microenvironment is one of the important risk element for bone metastasis in prostate cancer (PCa). The present study aimed to determine whether obesity-induced elevation in palmitic acid (PA), which is the most abundant of the free fatty acid...

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Bibliographic Details
Main Authors: Jingzhou Wang, Jie Liu, Chenggang Yuan, Bingqi Yang, Huai Pang, Keru Chen, Jiale Feng, Yuchun Deng, Xueting Zhang, Wei Li, Cuizhe Wang, Jianxin Xie, Jun Zhang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
Palmitic acid
Bone marrow adipocytes
GPRs/KLF7/CCL2
Prostate cancer
Online Access:https://doi.org/10.1186/s12885-024-11826-5

Internet

https://doi.org/10.1186/s12885-024-11826-5

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