STUDY OF THE SEVERITY AND EARLY ANTIVIRAL TREATMENT FOR THE DURATION OF THE RECOVERY COVID-19 PATIENTS

Late antiviral treatment can potentially cause the Covid-19 virus to replicate very quickly, so it is necessary to understand antiviral drugs and optimize treatment for Covid-19 patients. The study aimed to determine the correlation between the severity, speed of administration of antivirals, and t...

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Main Authors: Rinto Susilo, Tomi _, Nur Rahmi Hidayati, Deani Asmarandani, Daffa Fadhilah
Format: Article
Language:Indonesian
Published: Universitas Muhammadiyah Magelang 2023-01-01
Series:Jurnal Farmasi Sains dan Praktis
Subjects:
Online Access:http://journal.unimma.ac.id/index.php/pharmacy/article/view/7916
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author Rinto Susilo
Tomi _
Nur Rahmi Hidayati
Deani Asmarandani
Daffa Fadhilah
author_facet Rinto Susilo
Tomi _
Nur Rahmi Hidayati
Deani Asmarandani
Daffa Fadhilah
author_sort Rinto Susilo
collection DOAJ
description Late antiviral treatment can potentially cause the Covid-19 virus to replicate very quickly, so it is necessary to understand antiviral drugs and optimize treatment for Covid-19 patients. The study aimed to determine the correlation between the severity, speed of administration of antivirals, and the recovery time of Covid-19 patients. This type of research is an observational study with retrospective data collection on 94 Covid-19 medical records at “X” Hospital Cirebon from 316 populations in June-July 2021 according to inclusion criteria. The data analysis used was univariate and bivariate using Spearman's Rho. The 55–59-year age group (28.7%) was the most infected with Covid-19. There are more males than females (52.1% vs 47.9%). Favipiravir therapy (43.6%) was given the most. Moderate severity (74.5%) had the highest proportion. The speed of administration of antivirals was most initiated at 5-8 days (42.6%) after the onset of symptoms. The maximum recovery time for Covid-19 patients is 13-18 days (58.5%). A strong positive correlation between the speed of giving antivirals to the recovery time of Covid-19 patients (sig. 0.000) and the correlation coefficient of 0.659. Does not show a correlation between the severity of recovery time (sig. 0.113) and speed of antiviral administration to the severity of Covid-19 patients (sig. 0.297). There is a correlation between the early antiviral treatment and the recovery time of Covid-19 patients; the earlier antiviral therapy is given, the faster it will heal.
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spelling doaj.art-8797cd345d6e4b69b1c73ed24e5d01f52023-01-31T17:59:16ZindUniversitas Muhammadiyah MagelangJurnal Farmasi Sains dan Praktis2549-90682579-45582023-01-019110.31603/pharmacy.v9i1.7916STUDY OF THE SEVERITY AND EARLY ANTIVIRAL TREATMENT FOR THE DURATION OF THE RECOVERY COVID-19 PATIENTSRinto Susilo0Tomi _1Nur Rahmi Hidayati2Deani Asmarandani3Daffa Fadhilah4Pharmacy Undergraduate Study Program, School of Pharmacy Muhammadiyah Cirebon, West Java 45153, IndonesiaPharmacy Diploma III Study Program, School of Pharmacy Muhammadiyah Cirebon, West Java 45153, IndonesiaPharmacy Undergraduate Study Program, School of Pharmacy Muhammadiyah Cirebon, West Java 45153, IndonesiaPharmacy Undergraduate Study Program, School of Pharmacy Muhammadiyah Cirebon, West Java 45153, IndonesiaPharmacy Undergraduate Study Program, School of Pharmacy Muhammadiyah Cirebon, West Java 45153, Indonesia Late antiviral treatment can potentially cause the Covid-19 virus to replicate very quickly, so it is necessary to understand antiviral drugs and optimize treatment for Covid-19 patients. The study aimed to determine the correlation between the severity, speed of administration of antivirals, and the recovery time of Covid-19 patients. This type of research is an observational study with retrospective data collection on 94 Covid-19 medical records at “X” Hospital Cirebon from 316 populations in June-July 2021 according to inclusion criteria. The data analysis used was univariate and bivariate using Spearman's Rho. The 55–59-year age group (28.7%) was the most infected with Covid-19. There are more males than females (52.1% vs 47.9%). Favipiravir therapy (43.6%) was given the most. Moderate severity (74.5%) had the highest proportion. The speed of administration of antivirals was most initiated at 5-8 days (42.6%) after the onset of symptoms. The maximum recovery time for Covid-19 patients is 13-18 days (58.5%). A strong positive correlation between the speed of giving antivirals to the recovery time of Covid-19 patients (sig. 0.000) and the correlation coefficient of 0.659. Does not show a correlation between the severity of recovery time (sig. 0.113) and speed of antiviral administration to the severity of Covid-19 patients (sig. 0.297). There is a correlation between the early antiviral treatment and the recovery time of Covid-19 patients; the earlier antiviral therapy is given, the faster it will heal. http://journal.unimma.ac.id/index.php/pharmacy/article/view/7916Covid-19Early antiviral treatmentSeverityDuration of recovery
spellingShingle Rinto Susilo
Tomi _
Nur Rahmi Hidayati
Deani Asmarandani
Daffa Fadhilah
STUDY OF THE SEVERITY AND EARLY ANTIVIRAL TREATMENT FOR THE DURATION OF THE RECOVERY COVID-19 PATIENTS
Jurnal Farmasi Sains dan Praktis
Covid-19
Early antiviral treatment
Severity
Duration of recovery
title STUDY OF THE SEVERITY AND EARLY ANTIVIRAL TREATMENT FOR THE DURATION OF THE RECOVERY COVID-19 PATIENTS
title_full STUDY OF THE SEVERITY AND EARLY ANTIVIRAL TREATMENT FOR THE DURATION OF THE RECOVERY COVID-19 PATIENTS
title_fullStr STUDY OF THE SEVERITY AND EARLY ANTIVIRAL TREATMENT FOR THE DURATION OF THE RECOVERY COVID-19 PATIENTS
title_full_unstemmed STUDY OF THE SEVERITY AND EARLY ANTIVIRAL TREATMENT FOR THE DURATION OF THE RECOVERY COVID-19 PATIENTS
title_short STUDY OF THE SEVERITY AND EARLY ANTIVIRAL TREATMENT FOR THE DURATION OF THE RECOVERY COVID-19 PATIENTS
title_sort study of the severity and early antiviral treatment for the duration of the recovery covid 19 patients
topic Covid-19
Early antiviral treatment
Severity
Duration of recovery
url http://journal.unimma.ac.id/index.php/pharmacy/article/view/7916
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AT nurrahmihidayati studyoftheseverityandearlyantiviraltreatmentforthedurationoftherecoverycovid19patients
AT deaniasmarandani studyoftheseverityandearlyantiviraltreatmentforthedurationoftherecoverycovid19patients
AT daffafadhilah studyoftheseverityandearlyantiviraltreatmentforthedurationoftherecoverycovid19patients