PDX-1: A Promising Therapeutic Target to Reverse Diabetes

PDX-1: A Promising Therapeutic Target to Reverse Diabetes

The pancreatic duodenum homeobox-1 (<i>PDX-1</i>) is a transcription factor encoded by a Hox-like homeodomain gene that plays a crucial role in pancreatic development, β-cell differentiation, and the maintenance of mature β-cell functions. Research on the relationship between <i>PD...

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Bibliographic Details
Main Authors: Yanjiao Zhang, Xinyi Fang, Jiahua Wei, Runyu Miao, Haoran Wu, Kaile Ma, Jiaxing Tian
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomolecules
Subjects:
<i>PDX-1</i>
diabetes mellitus
reversal
transcription factor
β-cell
Online Access:https://www.mdpi.com/2218-273X/12/12/1785

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