Cdk8 and Ssn801 Regulate Oxidative Stress Resistance and Virulence in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

Cdk8 and Ssn801 Regulate Oxidative Stress Resistance and Virulence in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

ABSTRACT Cryptococcus neoformans kills 200,000 people worldwide each year. After inhalation, this environmental yeast proliferates either extracellularly or within host macrophages. Under conditions of immunocompromise, cryptococci disseminate from the lungs to the brain, causing a deadly meningoenc...

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Bibliographic Details
Main Authors: Andrew L. Chang, Yiming Kang, Tamara L. Doering
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mBio
Subjects:
Cdk8
Cryptococcus neoformans
Mediator complex
Ssn801
mitochondria
Online Access:https://journals.asm.org/doi/10.1128/mBio.02818-18

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